New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS | |
Zhao Heng-Qiang1,2; Chen Jun-Hui1; Shi Qian1; Li Xin1; Cao Wei1; Li Jing-Xi1; Wang Xiao-Ru1,3 | |
刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
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2012-01-10 | |
卷号 | 33期号:1页码:44-48 |
关键词 | Nucleoside Animal drug Fingerprint Hydrophilic interaction liquid chromatography(HILIC) Time of flight-mass spectrometry(TOF/MS) |
ISSN号 | 0251-0790 |
DOI | 10.3969/j.issn.0251-0790.2012.01.007 |
英文摘要 | The feasibility of identification of the authenticity for various marine animal drugs was investigated by a fingerprinting method based on the distribution of nucleoside compounds, and a new method for the discrimination of precious animal drugs was provided. Sixteen nucleoside compounds in various marine animal drugs were determined by hydrophilic interaction liguid chromatography-electrospray ionization-time of flight-mass spectrometry(HILIC-ESI-TOF/MS). Characteristic fingerprint based on the distribution of 16 nucleosides was constructed, and it was used for identification of the authenticity of various marine animal drugs combined with similarity analysis and clustering analysis. The results indicated that the proposed characteristic fingerprint could reflect the inherent characteristics of their own for various marine animal drugs. Furthermore, it could be used to distinguish different marine animal drugs combined with similarity analysis and clustering analysis. In conclusion, the developed fingerprinting method is expected to be a powerful tool for the identification of animal drugs. |
WOS研究方向 | Chemistry |
语种 | 中文 |
出版者 | HIGHER EDUCATION PRESS |
WOS记录号 | WOS:000299715900007 |
内容类型 | 期刊论文 |
源URL | [http://ir.fio.com.cn/handle/2SI8HI0U/4145] ![]() |
专题 | 业务部门_海洋生态研究中心 |
作者单位 | 1.State Ocean Adm, Inst Oceanog 1, Qingdao Key Lab Analyt Technol Dev & Standardizat, Qingdao 266061, Peoples R China; 2.Ocean Univ China, Coll Chem & Chem Engn, Qingdao 266100, Peoples R China; 3.Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao Heng-Qiang,Chen Jun-Hui,Shi Qian,et al. New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2012,33(1):44-48. |
APA | Zhao Heng-Qiang.,Chen Jun-Hui.,Shi Qian.,Li Xin.,Cao Wei.,...&Wang Xiao-Ru.(2012).New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,33(1),44-48. |
MLA | Zhao Heng-Qiang,et al."New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 33.1(2012):44-48. |
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