Phenylquinolinones with antitumor activity from the Indian Ocean-derived fungus Aspergillus versicolor Y31-2

doi:10.1007/s00343-016-5097-y

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	Phenylquinolinones with antitumor activity from the Indian Ocean-derived fungus Aspergillus versicolor Y31-2
	Li Peihai; Fan Yaqin; Chen Hao; Chao Yaxi; Du Ning; Chen Junhui
刊名	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
	2016-09
卷号	34 期号:5 页码:1072-1075
关键词	phenylquinolinones anti-tumor Aspergillus versicolor
ISSN号	0254-4059
DOI	10.1007/s00343-016-5097-y
英文摘要	Two phenylquinolinones, including one new compound (1) and a previously isolated compound (2), were isolated from the ethyl acetate extracts of the fungus Aspergillus versicolor Y31-2, which was obtained from seawater samples collected from the Indian Ocean. The structures of these compounds were established by spectroscopic analyses. 4-(3-Hydroxyphenyl)-3-methoxyquinolin-2(1H)-one (1) exhibited moderate cytotoxicity against MCF-7 (human breast carcinoma cell line) and SMMC-7721 (human liver cancer cell line) cells with IC50 values of 16.6 and 18.2 mu mol/L, respectively. To the best of our knowledge, this study represents the first reported account of the isolation of compounds 1 and 2 as the secondary metabolites of the seawater derived fungus Aspergillus versicolor from the Indian Ocean.
资助项目	Basic Scientific Fund for National Public Research Institutes of China[GY0213G12]
WOS研究方向	Marine & Freshwater Biology ; Oceanography
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000379737000019
内容类型	期刊论文
源URL	[http://ir.fio.com.cn/handle/2SI8HI0U/3357]
专题	业务部门_海洋生态研究中心
作者单位	State Ocean Adm, Inst Oceanog 1, Key Lab Marine Bioact Subst, Qingdao 266000, Peoples R China
推荐引用方式 GB/T 7714	Li Peihai,Fan Yaqin,Chen Hao,et al. Phenylquinolinones with antitumor activity from the Indian Ocean-derived fungus Aspergillus versicolor Y31-2[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2016,34(5):1072-1075.
APA	Li Peihai,Fan Yaqin,Chen Hao,Chao Yaxi,Du Ning,&Chen Junhui.(2016).Phenylquinolinones with antitumor activity from the Indian Ocean-derived fungus Aspergillus versicolor Y31-2.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,34(5),1072-1075.
MLA	Li Peihai,et al."Phenylquinolinones with antitumor activity from the Indian Ocean-derived fungus Aspergillus versicolor Y31-2".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 34.5(2016):1072-1075.