Two new compounds from the broth of the marine fungus Penicillium griseofulvum Y19-07 | |
Wang, Ya-Nan1; Tian, Li2,3; Hua, Hui-Ming1; Lu, Xuan1; Sun, Sha1; Wu, Hong-Hua1; Pei, Yue-Hu1 | |
刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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2009 | |
卷号 | 11期号:11页码:912-917 |
关键词 | Penicillium griseofulvum marine fungus cytotoxicity |
ISSN号 | 1028-6020 |
DOI | 10.1080/10286020903219923 |
英文摘要 | Two new compounds, 4-hydroxyphenethyl methyl succinate (1) and 4-hydroxyphenethyl 2-(4-hydroxyphenyl)acetate (2), were isolated from the EtOAc extract of the broth of the marine fungus Penicillium griseofulvum Y19-07. Five known compounds were also obtained in this study. The structures of the new compounds were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry. All of the isolates were evaluated for their scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl free radical by spectroscopic assays. Also, in the cytotoxicity assay of the two new compounds against HL-60 and PC-3 prostate cancer cell lines, compound 2 showed potential activity with an IC50 value of 64.5 mu M against human HL-60 cancer cells. |
资助项目 | National Natural Science Foundation of China[40776098] |
WOS关键词 | NATURAL-PRODUCTS |
WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
出版者 | TAYLOR & FRANCIS LTD |
WOS记录号 | WOS:000273723800002 |
内容类型 | 期刊论文 |
源URL | [http://ir.fio.com.cn:8080/handle/2SI8HI0U/27461] ![]() |
专题 | 自然资源部第一海洋研究所 |
通讯作者 | Pei, Yue-Hu |
作者单位 | 1.Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China 2.First Inst Oceanog SOA, Qingdao 266061, Peoples R China 3.Qingdao Univ Sci & Technol, Dept Biol, Qingdao 266042, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Ya-Nan,Tian, Li,Hua, Hui-Ming,et al. Two new compounds from the broth of the marine fungus Penicillium griseofulvum Y19-07[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2009,11(11):912-917. |
APA | Wang, Ya-Nan.,Tian, Li.,Hua, Hui-Ming.,Lu, Xuan.,Sun, Sha.,...&Pei, Yue-Hu.(2009).Two new compounds from the broth of the marine fungus Penicillium griseofulvum Y19-07.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,11(11),912-917. |
MLA | Wang, Ya-Nan,et al."Two new compounds from the broth of the marine fungus Penicillium griseofulvum Y19-07".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 11.11(2009):912-917. |
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