Development of a quality evaluation system for Panax quinquefolium. L based on HPLC chromatographic fingerprinting of seven major ginsenosides

doi:10.1016/j.microc.2006.05.007

	Development of a quality evaluation system for Panax quinquefolium. L based on HPLC chromatographic fingerprinting of seven major ginsenosides
	Chen, Junhui ; Xie, Mingyong ; Fu, Zhihong ; Lee, Frank Sen-Chun ; Wang, Xiaoru
刊名	MICROCHEMICAL JOURNAL
	2007-04
卷号	85 期号:2 页码:201-208
关键词	high-performance liquid chromatography Panax quinquefolium. L ginsenoside quality evaluation system hierarchical clustering analysis
ISSN号	0026-265X
DOI	10.1016/j.microc.2006.05.007
英文摘要	A HPLC fingerprinting method based on the distribution and contents of seven major ginsenosides has been developed for the quality evaluation of Panax quinquefolium. L roots cultivated in China, Singapore and Canada. The method is ideally suited for the fingerprinting of P. quinquefolium. L samples or its derived products for sample authentication or quality control, e.g. pharmaceutical stability studies. Different extraction methods have been evaluated and a protocol established to maximize the gensinosides yields in routine operations. Hierarchical clustering analysis of the fingerprints demonstrates that the distribution and contents of ginsenosides in P quinquefolium. L root vary depending on geographic location; and the quality of Jilin-cultivated P quinquefolium. L roots is similar in composition to Canada-cultivated ones, which are generally considered among the best quality in P quinquefolium. L. (c) 2006 Elsevier B.V. All rights reserved.
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; QUANTITATIVE-DETERMINATION ; GINSENG PREPARATIONS ; ASSISTED EXTRACTION ; MASS-SPECTROMETRY ; AMERICAN GINSENG ; SAPONINS ; NOTOGINSENG ; ROOTS ; QUANTIFICATION
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000245321900003
内容类型	期刊论文
源URL	[http://ir.fio.com.cn:8080/handle/2SI8HI0U/27453]
专题	自然资源部第一海洋研究所
通讯作者	Xie, Mingyong
作者单位	1.Nanchang Univ, Minist Educ, Key Lab Food Sci, Nanchang 330047, Jiangxi, Peoples R China 2.Ocean Univ China, Coll Chem & Chem Engn, Qingdao 266003, Peoples R China 3.First Inst Oceanog SOA, QingDao Key Lab Analyt Technol Dev & Standardizat, Qingdao 266061, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Chen, Junhui,Xie, Mingyong,Fu, Zhihong,et al. Development of a quality evaluation system for Panax quinquefolium. L based on HPLC chromatographic fingerprinting of seven major ginsenosides[J]. MICROCHEMICAL JOURNAL,2007,85(2):201-208.
APA	Chen, Junhui,Xie, Mingyong,Fu, Zhihong,Lee, Frank Sen-Chun,&Wang, Xiaoru.(2007).Development of a quality evaluation system for Panax quinquefolium. L based on HPLC chromatographic fingerprinting of seven major ginsenosides.MICROCHEMICAL JOURNAL,85(2),201-208.
MLA	Chen, Junhui,et al."Development of a quality evaluation system for Panax quinquefolium. L based on HPLC chromatographic fingerprinting of seven major ginsenosides".MICROCHEMICAL JOURNAL 85.2(2007):201-208.