New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS

doi:10.3969/j.issn.0251-0790.2012.01.007

	New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS
	Zhao Heng-Qiang 1,2; Chen Jun-Hui 1; Shi Qian 1; Li Xin 1; Cao Wei 1; Li Jing-Xi 1; Wang Xiao-Ru 1,3
刊名	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
	2012-01-10
卷号	33 期号:1 页码:44-48
关键词	Nucleoside Animal drug Fingerprint Hydrophilic interaction liquid chromatography(HILIC) Time of flight-mass spectrometry(TOF/MS)
ISSN号	0251-0790
DOI	10.3969/j.issn.0251-0790.2012.01.007
英文摘要	The feasibility of identification of the authenticity for various marine animal drugs was investigated by a fingerprinting method based on the distribution of nucleoside compounds, and a new method for the discrimination of precious animal drugs was provided. Sixteen nucleoside compounds in various marine animal drugs were determined by hydrophilic interaction liguid chromatography-electrospray ionization-time of flight-mass spectrometry(HILIC-ESI-TOF/MS). Characteristic fingerprint based on the distribution of 16 nucleosides was constructed, and it was used for identification of the authenticity of various marine animal drugs combined with similarity analysis and clustering analysis. The results indicated that the proposed characteristic fingerprint could reflect the inherent characteristics of their own for various marine animal drugs. Furthermore, it could be used to distinguish different marine animal drugs combined with similarity analysis and clustering analysis. In conclusion, the developed fingerprinting method is expected to be a powerful tool for the identification of animal drugs.
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; CULTURED CORDYCEPS ; ACTIVE COMPONENTS ; QUALITY-CONTROL ; ANALOGS ; SEPARATION ; EXTRACTION ; INJECTION
WOS研究方向	Chemistry
语种	中文
出版者	HIGHER EDUCATION PRESS
WOS记录号	WOS:000299715900007
内容类型	期刊论文
源URL	[http://ir.fio.com.cn:8080/handle/2SI8HI0U/26745]
专题	自然资源部第一海洋研究所
通讯作者	Chen Jun-Hui
作者单位	1.State Ocean Adm, Inst Oceanog 1, Qingdao Key Lab Analyt Technol Dev & Standardizat, Qingdao 266061, Peoples R China 2.Ocean Univ China, Coll Chem & Chem Engn, Qingdao 266100, Peoples R China 3.Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China
推荐引用方式 GB/T 7714	Zhao Heng-Qiang,Chen Jun-Hui,Shi Qian,et al. New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2012,33(1):44-48.
APA	Zhao Heng-Qiang.,Chen Jun-Hui.,Shi Qian.,Li Xin.,Cao Wei.,...&Wang Xiao-Ru.(2012).New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,33(1),44-48.
MLA	Zhao Heng-Qiang,et al."New Fingerprinting Method Based on the Distribution of Nucleoside Compounds for Marine Animal Drugs by HILIC-ESI-TOF/MS".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 33.1(2012):44-48.