Analysis of the genetic diversity of the lymphocystis virus and its evolutionary relationship with its hosts

doi:10.1007/s11262-011-0646-0

	Analysis of the genetic diversity of the lymphocystis virus and its evolutionary relationship with its hosts
	Yan, Xiu-Ying 1; Wu, Zao-He 1; Jian, Ji-Chang 1; Lu, Yi-Shan 1; Sun, Xiu-qin 2
刊名	VIRUS GENES
	2011-12
卷号	43 期号:3 页码:358-366
关键词	Lymphocystis disease virus (LCDV) mcp gene cyt b gene Phylogenetic relationship Cospeciation
ISSN号	0920-8569
DOI	10.1007/s11262-011-0646-0
英文摘要	Lymphocystis disease virus (LCDV) is the causative agent of lymphocystis disease. In this study, the mcp gene of LCDV and the cyt b gene of the host fish were selected as molecular markers, and the phylogenetic relationships between LCDV and its host were analyzed. The 25 LCDV isolates examined in this study were attributed to seven LCDV genotypes: genotype I (LCDV-1), genotype II (LCDV-cn, etc.), genotype III (LCDV-rf), genotype IV (LCDV-rc and LCDV-sb), genotype V (LCDV-cb), genotype VI (LCDV-tl), and genotype VII (LCDV-sa). Genotype VII is a new genotype. LCDV1 was found to have differentiated first, followed by LCDV-rf; then LCDV-tl; LCDV-cb; and then LCDV-sa; and by LCDV-rc and LCDV-sb; and finally by LCDV-cn, LCDV-C, and LCDV-jf. From the host evolutionary perspective, Rachycentron canadum was found to have differentiated first, followed by Trichogaster leeri, Chanda baculis, and Sebastes schlegeli, Lateolabrax sp., Sparus aurata, Platichthys flesus, and Paralichthys olivaceus. Comparison of the phylogenies of the host fish species and LCDVs revealed no significant evidence of cospeciation between LCDVs and their host fish. In-depth studies of the genetic variation in LCDVs can enhance our understanding of the mechanism of LCDV infection, which may provide important insights into the prevention and treatment of lymphocystis disease.
资助项目	National Torch Program in China[2008GA780013]
WOS研究方向	Genetics & Heredity ; Virology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000295086200007
内容类型	期刊论文
源URL	[http://ir.fio.com.cn/handle/2SI8HI0U/4169]
专题	自然资源部第一海洋研究所
作者单位	1.Guangdong Ocean Univ, Guangdong Key Lab Pathogen Biol & Epidemiol Aquat, Zhanjiang 524025, Peoples R China; 2.First Inst Oceanog SOA, Qingdao 266061, Peoples R China
推荐引用方式 GB/T 7714	Yan, Xiu-Ying,Wu, Zao-He,Jian, Ji-Chang,et al. Analysis of the genetic diversity of the lymphocystis virus and its evolutionary relationship with its hosts[J]. VIRUS GENES,2011,43(3):358-366.
APA	Yan, Xiu-Ying,Wu, Zao-He,Jian, Ji-Chang,Lu, Yi-Shan,&Sun, Xiu-qin.(2011).Analysis of the genetic diversity of the lymphocystis virus and its evolutionary relationship with its hosts.VIRUS GENES,43(3),358-366.
MLA	Yan, Xiu-Ying,et al."Analysis of the genetic diversity of the lymphocystis virus and its evolutionary relationship with its hosts".VIRUS GENES 43.3(2011):358-366.