Recent advances in bulk metallic glasses for biomedical applications

doi:10.1016/j.actbio.2016.03.047

CORC > 北京大学 > 工学院

	Recent advances in bulk metallic glasses for biomedical applications
	Li, H. F. ; Zheng, Y. F.
刊名	ACTA BIOMATERIALIA
	2016
关键词	Bulk metallic glasses Liquid metal Advanced materials Biomaterials Clinical applications ZR65AL7.5NI10CU17.5 AMORPHOUS ALLOY IMMERSION ION-IMPLANTATION OPTIMIZING BONE-FORMATION VITRO CORROSION BEHAVIOR SIMULATED BODY-FLUID SHAPE-MEMORY ALLOY IN-VITRO MECHANICAL-PROPERTIES FORMING ABILITY SURFACE MODIFICATION
DOI	10.1016/j.actbio.2016.03.047
英文摘要	With a continuously increasing aging population and the improvement of living standards, large demands of biomaterials are expected for a long time to come. Further development of novel biomaterials, that are much safer and of much higher quality, in terms of both biomedical and mechanical properties, are therefore of great interest for both the research scientists and clinical surgeons. Compared with the conventional crystalline metallic counterparts, bulk metallic glasses have unique amorphous structures, and thus exhibit higher strength, lower Young's modulus, improved wear resistance, good fatigue endurance, and excellent corrosion resistance. For this purpose, bulk metallic glasses (BMGs) have recently attracted much attention for biomedical applications. This review discusses and summarizes the recent developments and advances of bulk metallic glasses, including Ti-based, Zr-based, Fe-based, Mg-based, Zn-based, Ca-based and Sr-based alloying systems for biomedical applications. Future research directions will move towards overcoming the brittleness, increasing the glass forming ability (GFA) thus obtaining corresponding bulk metallic glasses with larger sizes, removing/reducing toxic elements, and surface modifications. Statement of Significance Bulk metallic glasses (BMGs), also known as amorphous alloys or liquid metals, are relative newcomers in the field of biomaterials. They have gained increasing attention during the past decades, as they exhibit an excellent combination of properties and processing capabilities desired for versatile biomedical implant applications. The present work reviewed the recent developments and advances of biomedical BMGs, including Ti-based, Zr-based, Fe-based, Mg-based, Zn-based, Ca-based and Sr-based BMG alloying systems. Besides, the critical analysis and in-depth discussion on the current status, challenge and future development of biomedical BMGs are included. The possible solution to the BMG size limitation, the brittleness of BMGs has been proposed. (C) 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.; National Basic Research Program of China (973 Program) [2012CB619102]; National Science Fund for Distinguished Young Scholars [51225101]; National Natural Science Foundation of China [51431002, 31170909]; NSFC/RGC Joint Research Scheme [51361165101]; Beijing Municipal Science and Technology Project [Z141100002814008]; SCI(E); PubMed; REVIEW; yfzheng@pku.edu.cn; 1-20; 36
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/434242]
专题	工学院
推荐引用方式 GB/T 7714	Li, H. F.,Zheng, Y. F.. Recent advances in bulk metallic glasses for biomedical applications[J]. ACTA BIOMATERIALIA,2016.
APA	Li, H. F.,&Zheng, Y. F..(2016).Recent advances in bulk metallic glasses for biomedical applications.ACTA BIOMATERIALIA.
MLA	Li, H. F.,et al."Recent advances in bulk metallic glasses for biomedical applications".ACTA BIOMATERIALIA (2016).