Frequency-Dependent Modulation of Regional Synchrony in the Human Brain   by Eyes Open and Eyes Closed Resting-States

doi:10.1371/journal.pone.0141507

CORC > 北京大学 > 工学院

	Frequency-Dependent Modulation of Regional Synchrony in the Human Brain by Eyes Open and Eyes Closed Resting-States
	Song, Xiaopeng ; Zhou, Shuqin ; Zhang, Yi ; Liu, Yijun ; Zhu, Huaiqiu ; Gao, Jia-Hong
刊名	PLOS ONE
	2015
关键词	AMPLITUDE
DOI	10.1371/journal.pone.0141507
英文摘要	The eyes-open (EO) and eyes-closed (EC) states have differential effects on BOLD-fMRI signal dynamics, affecting both the BOLD oscillation frequency of a single voxel and the regional homogeneity (ReHo) of several neighboring voxels. To explore how the two resting- states modulate the local synchrony through different frequency bands, we decomposed the time series of each voxel into several components that fell into distinct frequency bands. The ReHo in each of the bands was calculated and compared between the EO and EC conditions. The cross-voxel correlations between the mean frequency and the overall ReHo of each voxel's original BOLD series in different brain areas were also calculated and compared between the two states. Compared with the EC state, ReHo decreased with EO in a wide frequency band of 0.01-0.25 Hz in the bilateral thalamus, sensorimotor network, and superior temporal gyrus, while ReHo increased significantly in the band of 0-0.01 Hz in the primary visual cortex, and in a higher frequency band of 0.02-0.1 Hz in the higher order visual areas. The cross-voxel correlations between the frequency and overall ReHo were negative in all the brain areas but varied from region to region. These correlations were stronger with EO in the visual network and the default mode network. Our results suggested that different frequency bands of ReHo showed different sensitivity to the modulation of EO-EC states. The better spatial consistency between the frequency and overall ReHo maps indicated that the brain might adopt a stricter frequency-dependent configuration with EO than with EC.; National Natural Science Foundation of China [61131003, 81271549, 61431013, 81470816, 81430037, 31421003, 81227003]; China's National Strategic Basic Research Program (973) [2012CB720700]; SCI(E); PubMed; ARTICLE; jgao@pku.edu.cn; 11; e0141507; 10
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/417037]
专题	工学院
推荐引用方式 GB/T 7714	Song, Xiaopeng,Zhou, Shuqin,Zhang, Yi,et al. Frequency-Dependent Modulation of Regional Synchrony in the Human Brain by Eyes Open and Eyes Closed Resting-States[J]. PLOS ONE,2015.
APA	Song, Xiaopeng,Zhou, Shuqin,Zhang, Yi,Liu, Yijun,Zhu, Huaiqiu,&Gao, Jia-Hong.(2015).Frequency-Dependent Modulation of Regional Synchrony in the Human Brain by Eyes Open and Eyes Closed Resting-States.PLOS ONE.
MLA	Song, Xiaopeng,et al."Frequency-Dependent Modulation of Regional Synchrony in the Human Brain by Eyes Open and Eyes Closed Resting-States".PLOS ONE (2015).