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	Area stenosis associated with non-invasive fractional flow reserve obtained from coronary CT images
	Zhang, Jun-Mei ; Luo, Tong ; Huo, Yunlong ; Wan, Min ; Chua, Terrance ; Tan, Ru San ; Kassab, Ghassan S. ; Tan, Swee Yaw ; Zhong, Liang
	2013
DOI	10.1109/EMBC.2013.6610388
英文摘要	Fractional flow reserve (FFR) determined by invasive angiography is the gold standard to assess the severity of coronary artery disease (CAD). FFRCT can be obtained non-invasively by combining computed tomography (CT) images and Computational Fluid Dynamics (CFD) method. In this study, FFRCT was computed for 6 models of patient-specific left coronary artery trees reconstructed from CT images. A total of 12 stenoses were observed. FFR values obtained for 7 of the 12 stenoses during invasive angiography were used as the gold standard for comparison. On a per-stenosis basis, the sensitivity, specificity, positive predictive value and negative predictive value were 50%, 100%, 100% and 83.3% respectively for FFRCT. A weak correlation was found between percent lumen diameter stenosis and FFRCT (r=0.431; p>0.05). However, the correlation between percent lumen area stenosis and FFRCT was significant (r=0.853; pCT appears to be a promising index to assess the severity of CAD and lumen area has distinct advantages over diameter measurement in terms of anatomy assessment. ? 2013 IEEE.; EI; 0
语种	英语
内容类型	会议论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/411642]
专题	工学院
推荐引用方式 GB/T 7714	Zhang, Jun-Mei,Luo, Tong,Huo, Yunlong,et al. Area stenosis associated with non-invasive fractional flow reserve obtained from coronary CT images[C]. 见:.

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