Hierarchical structure analysis describing abnormal base composition of genomes

doi:10.1103/PhysRevE.72.041915

CORC > 北京大学 > 工学院

	Hierarchical structure analysis describing abnormal base composition of genomes
	Ouyang Zhengqing ; Liu Jian-Kun ; She Zhen-Su
刊名	physical review e statistical nonlinear and soft matter physics
	2005
DOI	10.1103/PhysRevE.72.041915
英文摘要	Abnormal base compositional patterns of genomic DNA sequences are studied in the framework of a hierarchical structure (HS) model originally proposed for the study of fully developed turbulence [She and Lévêque, Phys. Rev. Lett. 72, 336 (1994)]. The HS similarity law is verified over scales between 10(3)bp and 10(5)bp, and the HS parameter beta is proposed to describe the degree of heterogeneity in the base composition patterns. More than one hundred bacteria, archaea, virus, yeast, and human genome sequences have been analyzed and the results show that the HS analysis efficiently captures abnormal base composition patterns, and the parameter beta is a characteristic measure of the genome. Detailed examination of the values of beta reveals an intriguing link to the evolutionary events of genetic material transfer. Finally, a sequence complexity (S) measure is proposed to characterize gradual increase of organizational complexity of the genome during the evolution. The present study raises several interesting issues in the evolutionary history of genomes.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000232930600078&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; SCI(E); EI; PubMed; 2; 4 Pt 1; 041915; 72
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/346142]
专题	工学院
推荐引用方式 GB/T 7714	Ouyang Zhengqing,Liu Jian-Kun,She Zhen-Su. Hierarchical structure analysis describing abnormal base composition of genomes[J]. physical review e statistical nonlinear and soft matter physics,2005.
APA	Ouyang Zhengqing,Liu Jian-Kun,&She Zhen-Su.(2005).Hierarchical structure analysis describing abnormal base composition of genomes.physical review e statistical nonlinear and soft matter physics.
MLA	Ouyang Zhengqing,et al."Hierarchical structure analysis describing abnormal base composition of genomes".physical review e statistical nonlinear and soft matter physics (2005).