Surface Initiated Polymerization from Substrates of Low Initiator   Density and Its Applications in Biosensors

doi:10.1021/am1006832

CORC > 北京大学 > 工学院

	Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors
	Ma, Hongwei ; He, Jian&apos ; Liu, Xing ; Gan, Jianhong ; Jin, Gang ; Zhou, Jiahai ; an
刊名	acs applied materials interfaces
	2010
关键词	surface initiated polymerization biosensor matrix quartz crystal microbalance surface plasmon resonance protein microarray TRANSFER RADICAL POLYMERIZATION POLY(ETHYLENE GLYCOL) RESPONSIVE POLYMERS AQUEOUS ATRP BRUSHES PROTEIN GOLD POLY(DIMETHYLSILOXANE) FUNCTIONALIZATION ADSORPTION
DOI	10.1021/am1006832
英文摘要	Surface initiated polymerization (SIP) has become an attractive method for tailoring physical and chemical properties of surfaces for a broad range of applications. Most of those application relied on the merit of a high density coating. In this study we explored a long overlooked field of SIP. SIP from substrates of low initiator density. We combined ellipsometry with AFM to investigate the effect of initiatior density and polymerization time on the morphology of polymer coatings. In addition, we carefully adjusted the nanoscale separation of polymer chains to achieve a balance between nonfouling and immobilization capacities. We further tested the performance of those coating on various biosensors, such as quartz crystal microbalance, surface plasmon resonance, and protein microarrays. The optimized matrices enhanced the performance of those biosensors. This report shall encourage researches to explore new frontiers in SIP that go beyond polymer brushes.; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; SCI(E); EI; 27; ARTICLE; 11; 3223-3230; 2
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/241837]
专题	工学院
推荐引用方式 GB/T 7714	Ma, Hongwei,He, Jian&apos,Liu, Xing,et al. Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors[J]. acs applied materials interfaces,2010.
APA	Ma, Hongwei.,He, Jian&apos.,Liu, Xing.,Gan, Jianhong.,Jin, Gang.,...&an.(2010).Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors.acs applied materials interfaces.
MLA	Ma, Hongwei,et al."Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors".acs applied materials interfaces (2010).