Thirty minute transcutaneous electric acupoint stimulation modulates   resting state brain activities: A perfusion and BOLD fMRI study

doi:10.1016/j.brainres.2012.03.063

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	Thirty minute transcutaneous electric acupoint stimulation modulates resting state brain activities: A perfusion and BOLD fMRI study
	Jiang, Yin ; Hao, Ying ; Zhang, Yue ; Liu, Jing ; Wang, Xiaoying ; Han, Jisheng ; Fang, Jing ; Zhang, Jue ; Cui, Cailian
刊名	脑研究
	2012
关键词	Acupuncture Transcutaneous electric acupoint stimulation (TEAS) Sustained after effect Resting state Cerebral blood flow (CBF) Functional connectivity CEREBRAL-BLOOD-FLOW DEFAULT-MODE ACUPUNCTURE ANALGESIA FUNCTIONAL MRI CONNECTIVITY ANALYSIS NERVE-STIMULATION NEURAL RESPONSES PAIN NETWORK ELECTROACUPUNCTURE
DOI	10.1016/j.brainres.2012.03.063
英文摘要	Increasing neuroimaging studies have focused on the sustained after effects of acupuncture, especially for the changes of brain activities in rest. However, short-period stimuli have mostly been chosen in these works. The present study aimed to investigate how the resting state brain activities in healthy subjects were modulated by relatively long-period (30 min) acupuncture, a widely used modality in clinical practice. Transcutaneous electric acupoint stimulation (TEAS) or intermittent minimal TEAS (MTEAS) were given for 30 mm to 40 subjects. Functional MRI (fMRI) data were collected including the pre-stimulation resting state and the post-stimulation resting state, using dual-echo arterial spin labeling (ASL) techniques, representing both cerebral blood flow (CBF) signals and blood oxygen-dependent level (BOLD) signals simultaneously. Following 30 min TEAS, but not MTEAS, the mean global CBF decreased, and a significant decrease of regional CBF was observed in SI, insula, STG, MOG and IFG. Functional connectivity analysis showed more secure and spatially extended connectivity of both the DMN and. SMN after 30 mm TEAS. Our results implied that modulation of the regional brain activities and network connectivity induced by thirty minute TEAS may associate with the acupuncture-related therapeutic effects. Furthermore, the resting state regional CBF quantified by ASL perfusion fMRI may serve as a potential biomarker in future acupuncture studies. (C) 2012 Elsevier B.V. All rights reserved.; Neurosciences; SCI(E); PubMed; 10; ARTICLE; 13-25; 1457
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/191973]
专题	工学院
推荐引用方式 GB/T 7714	Jiang, Yin,Hao, Ying,Zhang, Yue,et al. Thirty minute transcutaneous electric acupoint stimulation modulates resting state brain activities: A perfusion and BOLD fMRI study[J]. 脑研究,2012.
APA	Jiang, Yin.,Hao, Ying.,Zhang, Yue.,Liu, Jing.,Wang, Xiaoying.,...&Cui, Cailian.(2012).Thirty minute transcutaneous electric acupoint stimulation modulates resting state brain activities: A perfusion and BOLD fMRI study.脑研究.
MLA	Jiang, Yin,et al."Thirty minute transcutaneous electric acupoint stimulation modulates resting state brain activities: A perfusion and BOLD fMRI study".脑研究 (2012).