An Efficient and Specific Protection of Non-Thermal Plasma-Induced Live   Yeast Cell Derivative (LYCD) for Cells against Plasma Damage

doi:10.1002/ppap.201300206

CORC > 北京大学 > 工学院

	An Efficient and Specific Protection of Non-Thermal Plasma-Induced Live Yeast Cell Derivative (LYCD) for Cells against Plasma Damage
	Ma, Ruonan ; Feng, Hongqing ; Guo, Jinsong ; Liang, Yongdong ; Zhang, Qian ; Tian, Ying ; Zhang, Jue ; Fang, Jing
刊名	plasma processes and polymers
	2014
关键词	live yeast cell derivatives non-thermal plasmas precaution agents protective effects reactive oxygen species BARRIER DISCHARGE PLASMA ATMOSPHERIC-PRESSURE OXIDATIVE STRESS SACCHAROMYCES-CEREVISIAE HYDROGEN-PEROXIDE GLUTATHIONE CATALASE COLD SKIN AIR
DOI	10.1002/ppap.201300206
英文摘要	With the development of plasma medicine, safety issues are emerging as a serious concern. In this study, the protective effects of live yeast cell derivative (LYCD) on yeast (Saccharomyces cerevisiae) and mammalian cells (NIH-3T3) subjected to plasma treatment were investigated. The anti-oxidative properties of LYCD were assessed by analyzing three important antioxidants: superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). The results show that LYCD can efficiently protect the S. cerevisiae and NIH-3T3 cells against plasma treatment by elevating the survival ratio from 7 to 60% and 10 to 60%, respectively, and reverse the increased intracellular reactive oxygen species production following plasma exposure. Additionally, the protection is shown to be specific when compared with UV and H2O2 treatment. SOD and CAT activities as well as GSH content of LYCD increase linearly with plasma induction time. Simultaneously, the LYCD protection efficacies are increasing with longer plasma induction time, indicating that SOD, CAT, and GSH all contribute to the protective effect of LYCD. This work suggests that the non-toxic LYCD can serve as a promising precaution agent to enhance the safety of plasma applied directly to human body in the future.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342961600002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Physics, Applied; Physics, Fluids & Plasmas; Physics, Condensed Matter; Polymer Science; SCI(E); EI; 2; ARTICLE; zhangjue@pku.edu.cn; 9; 822-832; 11
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/164106]
专题	工学院
推荐引用方式 GB/T 7714	Ma, Ruonan,Feng, Hongqing,Guo, Jinsong,et al. An Efficient and Specific Protection of Non-Thermal Plasma-Induced Live Yeast Cell Derivative (LYCD) for Cells against Plasma Damage[J]. plasma processes and polymers,2014.
APA	Ma, Ruonan.,Feng, Hongqing.,Guo, Jinsong.,Liang, Yongdong.,Zhang, Qian.,...&Fang, Jing.(2014).An Efficient and Specific Protection of Non-Thermal Plasma-Induced Live Yeast Cell Derivative (LYCD) for Cells against Plasma Damage.plasma processes and polymers.
MLA	Ma, Ruonan,et al."An Efficient and Specific Protection of Non-Thermal Plasma-Induced Live Yeast Cell Derivative (LYCD) for Cells against Plasma Damage".plasma processes and polymers (2014).