In vitro and in vivo studies on Ti-based bulk metallic glass as   potential dental implant material

doi:10.1016/j.msec.2013.04.038

CORC > 北京大学 > 工学院

	In vitro and in vivo studies on Ti-based bulk metallic glass as potential dental implant material
	Wang, Y. B. ; Li, H. F. ; Cheng, Y. ; Zheng, Y. F. ; Ruan, L. Q.
刊名	materials science engineering c materials for biological applications
	2013
关键词	TiZrHfCuNiSiSn alloy Bulk metallic glass In vitro In vivo BIOMEDICAL APPLICATIONS AMORPHOUS-ALLOYS FORMING ABILITY CYTOTOXICITY BIOCOMPATIBILITY IONS BEHAVIOR CELLS
DOI	10.1016/j.msec.2013.04.038
英文摘要	In this study, a high glass forming system, Ti41.5Zr2.5Hf5Cu37.5Ni7.5Si1Sn5 (TZHCNSS) bulk metallic glass (BMG), is studied in terms of microstructure, surface analysis, mechanical properties, corrosion resistance, in vitro cytotoxicity and in vivo biocompatibility. It is found that the as-prepared TZHCNSS samples are fully amorphous by XRD and TEM observations, as well as DSC curve. Comparing with pure Ti, TZHCNSS BMG shows superior mechanical properties with higher hardness and better wear resistance. Due to the oxide film formed on its surface, TZHCNSS BMG shows great corrosion resistance close to pure Ti in electrochemical measurements. The pitting corrosion potential in artificial saliva solution is much higher than that in SBF solution. The indirect and direct cytotoxicity results show that TZHCNSS extracts had obvious low cell viability on both L929 and NIH3T3 cells. However, the in vivo testing results proved that TZHCNSS BMG could integrate with bone tissue, showing excellent osseointegration. (c) 2013 Elsevier B.V. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320973000050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Materials Science, Biomaterials; SCI(E); EI; PubMed; 12; ARTICLE; 6; 3489-3497; 33
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/153890]
专题	工学院
推荐引用方式 GB/T 7714	Wang, Y. B.,Li, H. F.,Cheng, Y.,et al. In vitro and in vivo studies on Ti-based bulk metallic glass as potential dental implant material[J]. materials science engineering c materials for biological applications,2013.
APA	Wang, Y. B.,Li, H. F.,Cheng, Y.,Zheng, Y. F.,&Ruan, L. Q..(2013).In vitro and in vivo studies on Ti-based bulk metallic glass as potential dental implant material.materials science engineering c materials for biological applications.
MLA	Wang, Y. B.,et al."In vitro and in vivo studies on Ti-based bulk metallic glass as potential dental implant material".materials science engineering c materials for biological applications (2013).