Aptasensor for Staphylococcus Enterotoxin B Detection Using High SNR   Piezoresistive Microcantilevers

doi:10.1109/JMEMS.2014.2345666

CORC > 北京大学 > 信息科学技术学院

	Aptasensor for Staphylococcus Enterotoxin B Detection Using High SNR Piezoresistive Microcantilevers
	Zhao, Rui ; Wen, Yongzheng ; Yang, Jiancheng ; Zhang, Jianlin ; Yu, Xiaomei
刊名	journal of microelectromechanical systems
	2014
关键词	Aptamers aptasensor nanogold piezoresistive microcantilever staphylococcus enterotoxin B (SEB) SIZED CANTILEVER SENSORS IMMUNOASSAY IMMUNOSENSOR SENSITIVITY BIOSENSORS APTAMERS ARRAY MILK
DOI	10.1109/JMEMS.2014.2345666
英文摘要	This paper proposes and demonstrates aptasensors for the detections of staphylococcus enterotoxin B (SEB) both in buffer and skim milk by using thiol-modified piezoresistive microcantilever. With attempts to optimize the design and fabrication processes of the microcantilever, the signal-to-noise rate of the aptasensor was greatly improved and an output voltage shift smaller than 1 mu V was successfully obtained. By immobilizing thiol-modified target aptamers onto the nanogold-coated surface of the sensing cantilevers, different concentrations of SEB were detected with a wide detection range of 6-300 ng/mL in buffer, as well as in skim milk. All the experimental results indicate that the piezoresistive cantilever-based aptasensor has sufficient sensitivity to detect food contaminants and might provide an economical platform for on-site detections of different toxicants with the advantages of portability, high sensitivity, and rapid response. [2014-0088]; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343318500007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Engineering, Electrical & Electronic; Engineering, Mechanical; SCI(E); EI; 3; ARTICLE; zhaorui2012@pku.edu.cn; wenyzheng@pku.edu.cn; deric.jc.yang@gmail.com; terry.lim@163.com; yuxm@pku.edu.cn; 5; 1054-1062; 23
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/291531]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Zhao, Rui,Wen, Yongzheng,Yang, Jiancheng,et al. Aptasensor for Staphylococcus Enterotoxin B Detection Using High SNR Piezoresistive Microcantilevers[J]. journal of microelectromechanical systems,2014.
APA	Zhao, Rui,Wen, Yongzheng,Yang, Jiancheng,Zhang, Jianlin,&Yu, Xiaomei.(2014).Aptasensor for Staphylococcus Enterotoxin B Detection Using High SNR Piezoresistive Microcantilevers.journal of microelectromechanical systems.
MLA	Zhao, Rui,et al."Aptasensor for Staphylococcus Enterotoxin B Detection Using High SNR Piezoresistive Microcantilevers".journal of microelectromechanical systems (2014).