Fluorescent Nanoparticle Beacon for Logic Gate Operation Regulated by   Strand Displacement

doi:10.1021/am401493d

CORC > 北京大学 > 信息科学技术学院

	Fluorescent Nanoparticle Beacon for Logic Gate Operation Regulated by Strand Displacement
	Yang, Jing ; Shen, Lingjing ; Ma, Jingjing ; Schlaberg, H. Inaki ; Liu, Shi ; Xu, Jin ; Zhang, Cheng
刊名	acs applied materials interfaces
	2013
关键词	fluorescent nanoparticle beacon multilevel strand displacement cascaded logic gate TEM image fluorescent signals PAGE analysis GOLD NANOPARTICLES ENERGY-TRANSFER DNA CIRCUITS
DOI	10.1021/am401493d
英文摘要	A mechanism is developed to construct a logic system by employing DNA/gold nanoparticle (AuNP) conjugates as a basic work unit, utilizing a fluorescent beacon probe to detect output signals. To implement the logic circuit, a self-assembly DNA structure is attached onto nanoparticles to form the fluorescent beacon. Moreover, assisted by regulation of multilevel strand displacement, cascaded logic gates are achieved. The computing results are detected by methods using fluorescent signals, gel electrophoresis and transmission electron microscope (TEM). This work is expected to demonstrate the feasibility of the cascaded logic system based on fluorescent nanoparticle beacons, suggesting applications in DNA computation and biotechnology.; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; SCI(E); EI; 6; ARTICLE; 12; 5392-5396; 5
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/223351]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Yang, Jing,Shen, Lingjing,Ma, Jingjing,et al. Fluorescent Nanoparticle Beacon for Logic Gate Operation Regulated by Strand Displacement[J]. acs applied materials interfaces,2013.
APA	Yang, Jing.,Shen, Lingjing.,Ma, Jingjing.,Schlaberg, H. Inaki.,Liu, Shi.,...&Zhang, Cheng.(2013).Fluorescent Nanoparticle Beacon for Logic Gate Operation Regulated by Strand Displacement.acs applied materials interfaces.
MLA	Yang, Jing,et al."Fluorescent Nanoparticle Beacon for Logic Gate Operation Regulated by Strand Displacement".acs applied materials interfaces (2013).