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Microfluidic sterilization
Zhang, Rui ; Huang, Jie ; Xie, Fei ; Wang, Baojun ; Chu, Ming ; Wang, Yuedan ; Li, Haichao ; Wang, Wei ; Zhang, Haixia ; Wu, Wengang ; Li, Zhihong
刊名biomicrofluidics
2014
关键词TOTAL ANALYSIS SYSTEMS HIGH-PRESSURE CELL-CULTURE MICROREACTOR
DOI10.1063/1.4882776
英文摘要Nowadays, microfluidics is attracting more and more attentions in the biological society and has provided powerful solutions for various applications. This paper reported a microfluidic strategy for aqueous sample sterilization. A well-designed small microchannel with a high hydrodynamic resistance was used to function as an in-chip pressure regulator. The pressure in the upstream microchannel was thereby elevated which made it possible to maintain a boiling-free high temperature environment for aqueous sample sterilization. A 120 degrees C temperature along with a pressure of 400 kPa was successfully achieved inside the chip to sterilize aqueous samples with E. coli and Staphylococcus aureus inside. This technique will find wide applications in portable cell culturing, microsurgery in wild fields, and other related micro total analysis systems. (C) 2014 AIP Publishing LLC.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339004500019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemical Research Methods; Biophysics; Nanoscience & Nanotechnology; Physics, Fluids & Plasmas; SCI(E); EI; PubMed; 0; ARTICLE; w.wang@pku.edu.cn; 3; 034119; 8
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/156284]  
专题信息科学技术学院
推荐引用方式
GB/T 7714
Zhang, Rui,Huang, Jie,Xie, Fei,et al. Microfluidic sterilization[J]. biomicrofluidics,2014.
APA Zhang, Rui.,Huang, Jie.,Xie, Fei.,Wang, Baojun.,Chu, Ming.,...&Li, Zhihong.(2014).Microfluidic sterilization.biomicrofluidics.
MLA Zhang, Rui,et al."Microfluidic sterilization".biomicrofluidics (2014).
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