An integrated exposure assessment of phthalates for the general   population in China based on both exposure scenario and biomonitoring   estimation approaches

doi:10.1016/j.yrtph.2015.11.019

CORC > 北京大学 > 环境科学与工程学院

	An integrated exposure assessment of phthalates for the general population in China based on both exposure scenario and biomonitoring estimation approaches
	Cao, Yan ; Liu, Jianguo ; Liu, Yang ; Wang, Jie ; Hao, Xuewen
刊名	REGULATORY TOXICOLOGY AND PHARMACOLOGY
	2016
关键词	Phthalate Exposure assessment Exposure scenario approach Biomonitoring estimation approach METABOLITE LEVELS SUBTROPICAL CITY SCHOOL-CHILDREN DIETARY-INTAKE ACID ESTERS DEHP ASSOCIATION URINE RISKS BIS(2-ETHYLHEXYL)PHTHALATE
DOI	10.1016/j.yrtph.2015.11.019
英文摘要	The representativeness of available studies on integrated exposure assessment of phthalates for the general population in China is lacking. Based on an exhaustive review of the extensive monitoring data available for China, this study presents a large-scale estimation of exposure levels to three typical phthalates, di(2-ethylhexyl) phthalate (DEHP), di-n-butyl phthalate (DBP) and diisobutyl phthalate (DiBP), by applying both exposure scenario and biomonitoring estimation approaches. The respective median exposure levels from the exposure scenario and biomonitoring estimation approaches were 3.80, 3.02 and 1.00 mu g/kg bw/day and 3.38, 3.21 and 3.32 mu g/kg bw/day for DEHP, DBP and DiBP, which are acceptable levels of exposure with respect to current international guidelines. Evaluation results from the two approaches showed both similarities and differences among the different phthalates, making the exposure assessment comparable and more comprehensive. In terms of sources of exposure, food intake was the largest contributor, while indoor air exposure had greater contribution to the estimated daily intakes (EDIs) of DiBP than that of the other phthalates. Moreover, more attention should be paid to the higher exposure levels of phthalates in several intensively industrialized and urbanized areas, and the causes of the different exposure levels in the different regions need to be further explored. (C) 2015 Elsevier Inc. All rights reserved.; State Key Joint Laboratory of Environment Simulation and Pollution Control (Peking University) [13Z04ESPCP]; National Science Foundation of China [21206011]; Importation and Development of High-Caliber Talents Project of Beijing Municipal Institutions, The National Basic Research Program of China [IDHT201304084]; SCI(E); PubMed; ARTICLE; jgliu@pku.edu.cn; 34-41; 74
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/435932]
专题	环境科学与工程学院
推荐引用方式 GB/T 7714	Cao, Yan,Liu, Jianguo,Liu, Yang,et al. An integrated exposure assessment of phthalates for the general population in China based on both exposure scenario and biomonitoring estimation approaches[J]. REGULATORY TOXICOLOGY AND PHARMACOLOGY,2016.
APA	Cao, Yan,Liu, Jianguo,Liu, Yang,Wang, Jie,&Hao, Xuewen.(2016).An integrated exposure assessment of phthalates for the general population in China based on both exposure scenario and biomonitoring estimation approaches.REGULATORY TOXICOLOGY AND PHARMACOLOGY.
MLA	Cao, Yan,et al."An integrated exposure assessment of phthalates for the general population in China based on both exposure scenario and biomonitoring estimation approaches".REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016).