Toxicity of TiO2 Nanoparticles to Escherichia coli: Effects of Particle   Size, Crystal Phase and Water Chemistry

doi:10.1371/journal.pone.0110247

CORC > 北京大学 > 环境科学与工程学院

	Toxicity of TiO2 Nanoparticles to Escherichia coli: Effects of Particle Size, Crystal Phase and Water Chemistry
	Lin, Xiuchun ; Li, Jingyi ; Ma, Si ; Liu, Gesheng ; Yang, Kun ; Tong, Meiping ; Lin, Daohui
刊名	plos one
	2014
关键词	TITANIUM-DIOXIDE NANOPARTICLES PHOTOCATALYTIC DISINFECTION ZNO NANOPARTICLES AQUATIC ORGANISMS HUMIC-ACID PHOTOTOXICITY NANOMATERIALS EXPOSURE LIGHT ANTIBACTERIAL
DOI	10.1371/journal.pone.0110247
英文摘要	Controversial and inconsistent results on the eco-toxicity of TiO2 nanoparticles (NPs) are commonly found in recorded studies and more experimental works are therefore warranted to elucidate the nanotoxicity and its underlying precise mechanisms. Toxicities of five types of TiO2 NPs with different particle sizes (10 similar to 50 nm) and crystal phases were investigated using Escherichia coli as a test organism. The effect of water chemistry on the nanotoxicity was also examined. The antibacterial effects of TiO2 NPs as revealed by dose-effect experiments decreased with increasing particle size and rutile content of the TiO2 NPs. More bacteria could survive at higher solution pH (5.0-10.0) and ionic strength (50-200 mg L-1 NaCl) as affected by the anatase TiO2 NPs. The TiO2 NPs with anatase crystal structure and smaller particle size produced higher content of intracellular reactive oxygen species and malondialdehyde, in line with their greater antibacterial effect. Transmission electron microscopic observations showed the concentration buildup of the anatase TiO2 NPs especially those with smaller particle sizes on the cell surfaces, leading to membrane damage and internalization. These research results will shed new light on the understanding of ecological effects of TiO2 NPs.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343210300101&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Multidisciplinary Sciences; SCI(E); PubMed; 7; ARTICLE; lindaohui@zju.edu.cn; 10; e110247; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/188917]
专题	环境科学与工程学院
推荐引用方式 GB/T 7714	Lin, Xiuchun,Li, Jingyi,Ma, Si,et al. Toxicity of TiO2 Nanoparticles to Escherichia coli: Effects of Particle Size, Crystal Phase and Water Chemistry[J]. plos one,2014.
APA	Lin, Xiuchun.,Li, Jingyi.,Ma, Si.,Liu, Gesheng.,Yang, Kun.,...&Lin, Daohui.(2014).Toxicity of TiO2 Nanoparticles to Escherichia coli: Effects of Particle Size, Crystal Phase and Water Chemistry.plos one.
MLA	Lin, Xiuchun,et al."Toxicity of TiO2 Nanoparticles to Escherichia coli: Effects of Particle Size, Crystal Phase and Water Chemistry".plos one (2014).