In situ airborne virus inactivation by microwave irradiation

doi:10.1007/s11434-014-0171-3

CORC > 北京大学 > 环境科学与工程学院

	In situ airborne virus inactivation by microwave irradiation
	Wu, Yan ; Yao, Maosheng
刊名	科学通报英文版
	2014
关键词	MS2 virus Microwave irradiation Protein genes Inactivation INFLUENZA-VIRUS MICROORGANISMS TRANSMISSION BIOAEROSOLS DIVERSITY AEROSOLS LIQUID GENE MS2
DOI	10.1007/s11434-014-0171-3
英文摘要	Infectious diseases cause tremendous costs of both human and economy annually. Previously, we have studied the bacterial, fungal, and allergen aerosol inactivation by direct microwave irradiation. Here, we further investigated its effects on airborne viruses. MS2 coliphage used as a human model virus was aerosolized and exposed to the direct microwave irradiation for similar to 2 min at three different power levels (700, 385, and 119 W). In addition to the survival rate, the viral genes before and after the microwave treatments were also examined using PCR and gel electrophoresis. Direct exposure of airborne MS2 viruses to the microwave irradiation at 700 W for less than 2 min was shown to result in more than 90 % inactivation efficiency, about 65 % at medium power level (385 W), and 50 % at the lowest level (119 W). The aerosol inactivation rate followed a linear relationship with the microwave exposure time (R-2 = 0.9889). Scanning electron images revealed visible damages to the viral surface after the exposure. Damages were also observed to the viral RNA genes coding for coat proteins, among which the A protein gene was completely destroyed. This study demonstrated that even without the filtration the direct microwave irradiation could also achieve rapid inactivation of viral aerosols. The information obtained can provide useful guidance on the development of microwave-based viral threat mitigation solutions in a closed or semi-closed space.; Multidisciplinary Sciences; SCI(E); 0; ARTICLE; yao@pku.edu.cn; 13; 1438-1445; 59
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/158263]
专题	环境科学与工程学院
推荐引用方式 GB/T 7714	Wu, Yan,Yao, Maosheng. In situ airborne virus inactivation by microwave irradiation[J]. 科学通报英文版,2014.
APA	Wu, Yan,&Yao, Maosheng.(2014).In situ airborne virus inactivation by microwave irradiation.科学通报英文版.
MLA	Wu, Yan,et al."In situ airborne virus inactivation by microwave irradiation".科学通报英文版 (2014).