Similarities and differences in decision-making impairments between   autism spectrum disorder and schizophrenia

doi:10.3389/fnbeh.2015.00259

CORC > 北京大学 > 心理与认知科学学院

	Similarities and differences in decision-making impairments between autism spectrum disorder and schizophrenia
	Zhang, Long ; Tang, Jiulai ; Dong, Yi ; Ji, Yifu ; Tao, Rui ; Liang, Zhitu ; Chen, Jingsong ; Wu, Yun ; Wang, Kai
刊名	FRONTIERS IN BEHAVIORAL NEUROSCIENCE
	2015
关键词	autism spectrum disorder decision-making decision-making under ambiguity decision-making under risk Game of Dice Task Iowa Gambling Task schizophrenia IOWA GAMBLING TASK HIGH-FUNCTIONING AUTISM RISK CONDITIONS WORKING-MEMORY PERFORMANCE DISSOCIATION DEFICITS REWARD ASSOCIATIONS SELECTIONS
DOI	10.3389/fnbeh.2015.00259
英文摘要	Although individuals with autism spectrum disorders (ASD) and schizophrenia (SCH) share overlapping characteristics and may perform similarly on many cognitive tasks, cognitive dysfunctions common to both disorders do not necessarily share the same underlying mechanisms. Decision-making is currently a major research interest for both ASD and SCH. The aim of the present study was to make direct comparisons of decision-making and disorder-specific underlying neuropsychological mechanisms between the two disorders. Thirty-seven participants with ASD, 46 patients with SCH, and 80 healthy controls (HC) were assessed with the Iowa Gambling Task (IGT), which measures decision-making under ambiguity, and the Game of Dice Task (GDT), which measures decision making under risk. The results revealed that both the ASD and SOH groups had deficits for both the IGT and the GDT compared with the HC. More importantly, in the IGT, participants with ASD displayed a preference for deck A, indicating that they had more sensitivity to the magnitude of loss than to the frequency of loss, whereas patients with SOH displayed a preference for deck B, indicating that they showed more sensitivity to the frequency of loss than to the magnitude of loss. In the GDT, the impaired performance might be due to the deficits in executive functions in patients with SOH, whereas the impaired performance might be due to the deficits in feedback processing in participants with ASD. These findings demonstrate that there are similar impairments in decision-making tasks between ASD and SOH; however, these two disorders may have different impairment mechanisms.; Natural Science Foundation of China [91232717, 91432301]; SCI(E); PubMed; SSCI; ARTICLE; wangkai1964@126.com; 259; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/416156]
专题	心理与认知科学学院
推荐引用方式 GB/T 7714	Zhang, Long,Tang, Jiulai,Dong, Yi,et al. Similarities and differences in decision-making impairments between autism spectrum disorder and schizophrenia[J]. FRONTIERS IN BEHAVIORAL NEUROSCIENCE,2015.
APA	Zhang, Long.,Tang, Jiulai.,Dong, Yi.,Ji, Yifu.,Tao, Rui.,...&Wang, Kai.(2015).Similarities and differences in decision-making impairments between autism spectrum disorder and schizophrenia.FRONTIERS IN BEHAVIORAL NEUROSCIENCE.
MLA	Zhang, Long,et al."Similarities and differences in decision-making impairments between autism spectrum disorder and schizophrenia".FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015).