Precedence-effect-induced enhancement of prepulse inhibition in socially   reared but not isolation-reared rats

doi:10.3758/CABN.9.1.44

CORC > 北京大学 > 心理与认知科学学院

	Precedence-effect-induced enhancement of prepulse inhibition in socially reared but not isolation-reared rats
	Du, Yi ; Li, Jingyu ; Wu, Xihong ; Li, Liang
刊名	cognitive affective behavioral neuroscience
	2009
关键词	MEDIAL PREFRONTAL CORTEX DEFICIENT ATTENTIONAL MODULATION PERCEIVED SPATIAL SEPARATION POSTERIOR PARIETAL CORTEX SPRAGUE-DAWLEY RATS STARTLE RESPONSE ACOUSTIC STARTLE INFORMATIONAL MASKING TEMPORAL ACUITY SEROTONERGIC FUNCTION
DOI	10.3758/CABN.9.1.44
英文摘要	Attention to a prepulse presented shortly before a startling stimulus enhances prepulse inhibition (PPI) of startle in normal people, but not in schizophrenics. Fear conditioning for the prepulse enhances PPI in socially reared, but not isolation-reared, rats. In humans, selective attention to acoustic signals against masking can be facilitated by precedence-effect-induced perceived spatial separation between the signal and the masker. This study investigated whether perceived spatial separation between a prepulse and a noise masker enhances PPI in socially reared rats and isolation-reared rats. The results show that both PPI and conditioning-induced PPI enhancement were larger in socially reared rats than in isolation-reared rats. More important, in socially reared, but not isolation-reared, rats, a further PPI enhancement was induced by precedence-effect-induced perceived separation between a prepulse and a masker only after the prepulse became fear conditioned. Thus, perceived separation facilitates normal rats' attention to a conditioned prepulse and enhances PPI. Isolation rearing impairs rats' ability to attend to ecologically significant acoustic events.; Behavioral Sciences; Neurosciences; SCI(E); PubMed; SSCI; 10; REVIEW; 1; 44-58; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/345206]
专题	心理与认知科学学院
推荐引用方式 GB/T 7714	Du, Yi,Li, Jingyu,Wu, Xihong,et al. Precedence-effect-induced enhancement of prepulse inhibition in socially reared but not isolation-reared rats[J]. cognitive affective behavioral neuroscience,2009.
APA	Du, Yi,Li, Jingyu,Wu, Xihong,&Li, Liang.(2009).Precedence-effect-induced enhancement of prepulse inhibition in socially reared but not isolation-reared rats.cognitive affective behavioral neuroscience.
MLA	Du, Yi,et al."Precedence-effect-induced enhancement of prepulse inhibition in socially reared but not isolation-reared rats".cognitive affective behavioral neuroscience (2009).