Trace analysis of quinolone and fluoroquinolone antibiotics from   wastewaters by liquid chromatography-electrospray tandem mass   spectrometry

doi:10.1016/j.chroma.2008.10.090

CORC > 北京大学 > 城市与环境学院

	Trace analysis of quinolone and fluoroquinolone antibiotics from wastewaters by liquid chromatography-electrospray tandem mass spectrometry
	Xiao, Yang ; Chang, Hong ; Jia, Ai ; Hu, Jianying
刊名	journal of chromatography a
	2008
关键词	Quinolone and fluoroquinolone antibiotics Environmental analysis Matrix effects WCX cartridge cleanup LC-ESI-MS/MS SOLID-PHASE EXTRACTION SEWAGE-TREATMENT PLANTS WASTE-WATER FLUORESCENCE DETECTION RESISTANT CAMPYLOBACTER ESCHERICHIA-COLI PHARMACEUTICALS SAMPLES CIPROFLOXACIN TRIMETHOPRIM
DOI	10.1016/j.chroma.2008.10.090
英文摘要	A sensitive liquid chromatography-electrospray tandem mass spectrometry method, combined with solid-phase extraction and a weak cation exchange cartridge cleanup, was established for twenty quinolone and fluoroquinolone antibiotics (pipemidic acid, flerofloxacin, ofloxacin, pefloxacin, enoxacin, norfloxacin, ciprofloxacin, danofloxacin, enrofloxacin, lomefloxacin, difloxacin, sarafloxacin, gatifloxacin, sparfloxacin, moxifloxacin, cinoxacin, oxolinic acid, nalidixic acid, flumequine, and piromidic acid) in influent, effluent, and river waters. For the various water matrices considered, the overall recoveries were from 64% to 127% except for piromidic acid (27-33%), and no obvious matrix effect was observed. The method detection limits for the twenty target antibiotics in the influent, effluent, and surface water samples were 1.6-50 ng/L, 0.6-50 ng/L, and 0.8-50 ng/L, respectively. This method was applied to analyze residual quinolone and fluoroquinolone antibiotics in wastewater and surface water samples from Beijing, China. Eight antibiotics (12 (pipemidic acid)-1208 ng/L (ofloxacin)) were detected in wastewater, and seven (1.3 (lomefloxacin)-535 ng/L (ofloxacin)) were detected in surface water samples. Gatifloxacin, a 4th generation fluoroquinolone antibiotic, was detected for the first time in influent (111 ng/L), effluent (56 ng/L), and river water (16-42 ng/L). 2008 Elsevier B.V. All rights reserved.; Biochemical Research Methods; Chemistry, Analytical; SCI(E); EI; PubMed; 76; ARTICLE; 1-2; 100-108; 1214
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/160737]
专题	城市与环境学院
推荐引用方式 GB/T 7714	Xiao, Yang,Chang, Hong,Jia, Ai,et al. Trace analysis of quinolone and fluoroquinolone antibiotics from wastewaters by liquid chromatography-electrospray tandem mass spectrometry[J]. journal of chromatography a,2008.
APA	Xiao, Yang,Chang, Hong,Jia, Ai,&Hu, Jianying.(2008).Trace analysis of quinolone and fluoroquinolone antibiotics from wastewaters by liquid chromatography-electrospray tandem mass spectrometry.journal of chromatography a.
MLA	Xiao, Yang,et al."Trace analysis of quinolone and fluoroquinolone antibiotics from wastewaters by liquid chromatography-electrospray tandem mass spectrometry".journal of chromatography a (2008).