CYP1A mRNA expression in redeye mullets (Liza haematocheila) from Bohai Bay, China | |
An, Lihui ; Hu, Jianying ; Yang, Min ; Zheng, Binghui ; Wei, An ; Shang, Jingjing ; Zhao, Xingru | |
刊名 | marine pollution bulletin
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2011 | |
关键词 | Redeye mullet CYP1A Real-time quantitative PCR Pollutants POLYBROMINATED DIPHENYL ETHERS POLYCYCLIC AROMATIC-HYDROCARBONS MARINE FOOD-WEB EQUIVALENCY FACTORS TEFS NORTH CHINA ORGANOCHLORINE PESTICIDES POLYCHLORINATED BIPHENYL ORGANIC POLLUTANTS EROD ACTIVITY FISH |
DOI | 10.1016/j.marpolbul.2011.01.019 |
英文摘要 | Induction of cytochrome P4501A (CYP1A) has been used as a biomarker in fish for monitoring aromatic and organic contaminants. In this study, a partial of CYP1A gene in redeye mullet (Liza haematocheila) was isolated and sequenced, and then a real-time quantitative reverse-transcription polymerase chain reaction assay was developed for quantification of CYP1A mRNA normalized to beta-actin. The developed method was applied to detect CYP1A mRNA expression in redeye mullets collected from Nandaihe (reference site) and Dashentang (impacted site) in Bohai Bay, China. CYP1A mRNA expression values were significantly elevated in redeye mullets from Dashentang compared to a reference site - Nandaihe, which was correlated with the contents of different environmentally relevant pollutants in tissues, particularly with PCBs and PBDEs. (C) 2011 Elsevier Ltd. All rights reserved.; Environmental Sciences; Marine & Freshwater Biology; SCI(E); EI; PubMed; 14; ARTICLE; 4; 718-725; 62 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/160685] ![]() |
专题 | 城市与环境学院 |
推荐引用方式 GB/T 7714 | An, Lihui,Hu, Jianying,Yang, Min,et al. CYP1A mRNA expression in redeye mullets (Liza haematocheila) from Bohai Bay, China[J]. marine pollution bulletin,2011. |
APA | An, Lihui.,Hu, Jianying.,Yang, Min.,Zheng, Binghui.,Wei, An.,...&Zhao, Xingru.(2011).CYP1A mRNA expression in redeye mullets (Liza haematocheila) from Bohai Bay, China.marine pollution bulletin. |
MLA | An, Lihui,et al."CYP1A mRNA expression in redeye mullets (Liza haematocheila) from Bohai Bay, China".marine pollution bulletin (2011). |
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