Occurrence and fate of quinolone and fluoroquinolone antibiotics in a   municipal sewage treatment plant

doi:10.1016/j.watres.2011.10.055

CORC > 北京大学 > 城市与环境学院

	Occurrence and fate of quinolone and fluoroquinolone antibiotics in a municipal sewage treatment plant
	Jia, Ai ; Wan, Yi ; Xiao, Yang ; Hu, Jianying
刊名	水研究
	2012
关键词	Antibiotics Quinolone Fluoroquinolone Sorption Mass balance Sewage treatment plant TANDEM MASS-SPECTROMETRY SOLID-PHASE EXTRACTION WATER TREATMENT PLANTS LIQUID-CHROMATOGRAPHY WASTE-WATER ANTIBACTERIAL AGENTS ESCHERICHIA-COLI FLUORESCENCE DETECTION AQUATIC ENVIRONMENT TRACE ANALYSIS
DOI	10.1016/j.watres.2011.10.055
英文摘要	This study developed a method for analysis of nineteen quinolone and fluoroquinolone antibiotics (FQs) in sludge samples, and investigated the occurrence and fate of the FQs in a municipal sewage treatment plant (STP) with anaerobic, anoxic, and aerobic treatment processes. Eleven compounds, including pipemidic acid, fleroxacin, ofloxacin, norfloxacin, ciprofloxacin, enrofloxacin, lomefloxacin, sparfloxacin, gatifloxacin, moxifloxacin, and sarafloxacin (only in sludge), were detected in the STP. The predominance of ofloxacin and norfloxacin, followed by lomefloxacin, ciprofloxacin, gatifloxacin, and moxifloxacin, were found in wastewater, suspended solids, and sludge. The total concentrations of FQs were 2573 +/- 241 ng/L, 1013 +/- 218 ng/L, and 18.4 +/- 0.9 mg/kg in raw sewage, secondary effluent, and sludge, respectively. Extremely low mass change percentages were observed for FQs in anaerobic, anoxic, and aerobic treatment units, suggesting biodegradation to be of minor importance in the removal of FQs in STPs. 50-87% of the initial FQs loadings (except for pipemidic acid (36%)) were ultimately found in the dewatered sludge. Mean removal efficiencies of FQs in the STP were 56-75%, except for new generation drugs such as moxifloxacin (40 +/- 5%) and gatifloxacin (43 +/- 13%). A significant positive correlation was found between removal efficiencies and K-d of FQs. The major factor in the removal of FQs in the STP was sorption to sludge, which was not governed by hydrophobic interactions. The long-term cycling and persistence of FQs in the STP has made activated sludge as a huge reservoir of FQ antibiotics. (C) 2011 Elsevier Ltd. All rights reserved.; Engineering, Environmental; Environmental Sciences; Water Resources; SCI(E); EI; PubMed; 61; ARTICLE; 2; 387-394; 46
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/160656]
专题	城市与环境学院
推荐引用方式 GB/T 7714	Jia, Ai,Wan, Yi,Xiao, Yang,et al. Occurrence and fate of quinolone and fluoroquinolone antibiotics in a municipal sewage treatment plant[J]. 水研究,2012.
APA	Jia, Ai,Wan, Yi,Xiao, Yang,&Hu, Jianying.(2012).Occurrence and fate of quinolone and fluoroquinolone antibiotics in a municipal sewage treatment plant.水研究.
MLA	Jia, Ai,et al."Occurrence and fate of quinolone and fluoroquinolone antibiotics in a municipal sewage treatment plant".水研究 (2012).