Nucleosomes are targeted to stabilize stalled replication forks via the elicitation of chromatin compaction by stalled forks; Nucleosomes are targeted to stabilize stalled replication forks via the elicitation of chromatin compaction by stalled forks | |
Daochun Kong | |
2016 | |
关键词 | replication stabilize targeted compaction checkpoint eukaryotic Replication genomic instability collapse replication stabilize targeted compaction checkpoint eukaryotic Replication genomic instability collapse |
英文摘要 | Replication fork stalling frequently occurs during DNA replication in eukaryotic cells and destabilizes replication forks,which can cause profound genomic instability if the forks collapse.The intra-S-phase checkpoint,which mainly targets the replisome,is required to prevent stalled forks from collapsing.In this study,a new aspect of cellular regulation in which nucleosomes are primarily targeted to stabilize stalled; Replication fork stalling frequently occurs during DNA replication in eukaryotic cells and destabilizes replication forks,which can cause profound genomic instability if the forks collapse.The intra-S-phase checkpoint,which mainly targets the replisome,is required to prevent stalled forks from collapsing.In this study,a new aspect of cellular regulation in which nucleosomes are primarily targeted to stabilize stalled; 中国生物化学与分子生物学会; 1 |
语种 | 英语 |
出处 | 中国生物化学与分子生物学会2016年全国学术会议 |
内容类型 | 其他 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/479835] ![]() |
专题 | 生命科学学院 |
推荐引用方式 GB/T 7714 | Daochun Kong. Nucleosomes are targeted to stabilize stalled replication forks via the elicitation of chromatin compaction by stalled forks, Nucleosomes are targeted to stabilize stalled replication forks via the elicitation of chromatin compaction by stalled forks. 2016-01-01. |
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