GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor   Genes with Diverse Functions in Root Hair Development

doi:10.1105/tpc.15.00607

CORC > 北京大学 > 生命科学学院

	GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor Genes with Diverse Functions in Root Hair Development
	Lin, Qing ; Ohashi, Yohei ; Kato, Mariko ; Tsuge, Tomohiko ; Gu, Hongya ; Qu, Li-Jia ; Aoyama, Takashi
刊名	PLANT CELL
	2015
关键词	EPIDERMAL-CELL DIFFERENTIATION POSITIVE FEEDBACK LOOP RECEPTOR-LIKE KINASE ARABIDOPSIS ROOT TRICHOME DEVELOPMENT REGULATORY NETWORK LATERAL INHIBITION MECHANISM CONTROLS PATTERN-FORMATION LEAF DEVELOPMENT
DOI	10.1105/tpc.15.00607
英文摘要	The Arabidopsis thaliana GLABRA2 (GL2) gene encodes a transcription factor involved in the cell differentiation of various epidermal tissues. During root hair pattern formation, GL2 suppresses root hair development in non-hair cells, acting as a node between the gene regulatory networks for cell fate determination and cell differentiation. Despite the importance of GL2 function, its molecular basis remains obscure because the GL2 target genes leading to the network for cell differentiation are unknown. We identified five basic helix-loop-helix (bHLH) transcription factor genes (ROOT HAIR DEFECTIVE6 [RHD6], RHD6-LIKE1 [RSL1], RSL2, Lj-RHL1-LIKE1 [LRL1], and LRL2) as GL2 direct targets using transcriptional and posttranslational induction systems. Chromatin immunoprecipitation analysis confirmed GL2 binding to upstream regions of these genes in planta. Reporter gene analyses showed that these genes are expressed in various stages of root hair development and are suppressed by GL2 in non-hair cells. GL2 promoter-driven GFP fusions of LRL1 and LRL2, but not those of the other bHLH proteins, conferred root hair development on non-hair cells. These results indicate that GL2 directly suppresses bHLH genes with diverse functions in root hair development.; National Transgenic Research Project [2013ZX08009-002]; Japanese Society of Promotion of Science [NSFC-JSPS 31211140041]; Japanese Society for the Promotion of Science [26891013]; 111 Project; Natural Science Foundation of China; SCI(E); ARTICLE; qulj@pku.edu.cn; aoyama@scl.kyoto-u.ac.jp; 10; 2894-2906; 27
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/439389]
专题	生命科学学院
推荐引用方式 GB/T 7714	Lin, Qing,Ohashi, Yohei,Kato, Mariko,et al. GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor Genes with Diverse Functions in Root Hair Development[J]. PLANT CELL,2015.
APA	Lin, Qing.,Ohashi, Yohei.,Kato, Mariko.,Tsuge, Tomohiko.,Gu, Hongya.,...&Aoyama, Takashi.(2015).GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor Genes with Diverse Functions in Root Hair Development.PLANT CELL.
MLA	Lin, Qing,et al."GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor Genes with Diverse Functions in Root Hair Development".PLANT CELL (2015).