Low Genetic Diversity and Strong Geographical Structure of the   Critically Endangered White-Headed Langur (Trachypithecus leucocephalus)   Inferred from Mitochondrial DNA Control Region Sequences

doi:10.1371/journal.pone.0129782

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	Low Genetic Diversity and Strong Geographical Structure of the Critically Endangered White-Headed Langur (Trachypithecus leucocephalus) Inferred from Mitochondrial DNA Control Region Sequences
	Wang, Weiran ; Qiao, Yu ; Pan, Wenshi ; Yao, Meng
刊名	PLOS ONE
	2015
关键词	EFFECTIVE POPULATION-SIZE SEX-BIASED DISPERSAL STATISTICAL TESTS KARST HILLS CONSERVATION IDENTIFICATION MANAGEMENT SELECTION MONKEYS CHINA
DOI	10.1371/journal.pone.0129782
英文摘要	Many Asian colobine monkey species are suffering from habitat destruction and population size decline. There is a great need to understand their genetic diversity, population structure and demographic history for effective species conservation. The white-headed langur (Trachypithecus leucocephalus) is a Critically Endangered colobine species endemic to the limestone karst forests in southwestern China. We analyzed the mitochondrial DNA (mtDNA) control region sequences of 390 fecal samples from 40 social groups across the main distribution areas, which represented one-third of the total extant population. Only nine haplotypes and 10 polymorphic sites were identified, indicating remarkably low genetic diversity in the species. Using a subset of 77 samples from different individuals, we evaluated genetic variation, population structure, and population demographic history. We found very low values of haplotype diversity (h = 0.570 +/- 0.056) and nucleotide diversity (pi = 0.00323 +/- 0.00044) in the hypervariable region I (HVRI) of the mtDNA control region. Distribution of haplotypes displayed marked geographical pattern, with one population (Chong-zuo, CZ) showing a complete lack of genetic diversity (having only one haplotype), whereas the other population (Fusui, FS) having all nine haplotypes. We detected strong population genetic structure among habit patches (phi(ST) = 0.375, P < 0.001). In addition, the Mantel test showed a significant correlation between the pairwise genetic distances and geographical distances among social groups in FS (correlation coefficient = 0.267, P = 0.003), indicting isolation-by-distance pattern of genetic divergence in the mtDNA sequences. Analyses of demographic history suggested an overall stable historical population size and modest population expansion in the last 2,000 years. Our results indicate different genetic diversity and possibly distinct population history for different local populations, and suggest that CZ and FS should be considered as one evolutionarily significant unit (ESU) and two management units (MUs) pending further investigation using nuclear markers.; National Natural Science Foundataion of China [31272329]; SCI(E); PubMed; ARTICLE; yaom@pku.edu.cn; 6; e0129782; 10
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/419388]
专题	生命科学学院
推荐引用方式 GB/T 7714	Wang, Weiran,Qiao, Yu,Pan, Wenshi,et al. Low Genetic Diversity and Strong Geographical Structure of the Critically Endangered White-Headed Langur (Trachypithecus leucocephalus) Inferred from Mitochondrial DNA Control Region Sequences[J]. PLOS ONE,2015.
APA	Wang, Weiran,Qiao, Yu,Pan, Wenshi,&Yao, Meng.(2015).Low Genetic Diversity and Strong Geographical Structure of the Critically Endangered White-Headed Langur (Trachypithecus leucocephalus) Inferred from Mitochondrial DNA Control Region Sequences.PLOS ONE.
MLA	Wang, Weiran,et al."Low Genetic Diversity and Strong Geographical Structure of the Critically Endangered White-Headed Langur (Trachypithecus leucocephalus) Inferred from Mitochondrial DNA Control Region Sequences".PLOS ONE (2015).