ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC   ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate   Immunity in Arabidopsis

doi:10.1105/tpc.108.065193

CORC > 北京大学 > 生命科学学院

	ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate Immunity in Arabidopsis
	Chen, Huamin ; Xue, Li ; Chintamanani, Satya ; Germain, Hugo ; Lin, Huiqiong ; Cui, Haitao ; Cai, Run ; Zuo, Jianru ; Tang, Xiaoyan ; Li, Xin ; Guo, Hongwei ; Zhou, Jian-Min
刊名	plant cell
	2009
关键词	SYSTEMIC ACQUIRED-RESISTANCE RESPONSE PATHWAY SALICYLIC-ACID SIGNAL-TRANSDUCTION DISEASE RESISTANCE DEFENSE RESPONSES PSEUDOMONAS ACTIVATION THALIANA MUTANTS
DOI	10.1105/tpc.108.065193
英文摘要	Pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) trigger plant immunity that forms the first line inducible defenses in plants. The regulatory mechanism of MAMP-triggered immunity, however, is poorly understood. Here, we show that Arabidopsis thaliana transcription factors ETHYLENE INSENSITIVE3 (EIN3) and ETHYLENE INSENSITIVE3-LIKE1 (EIL1), previously known to mediate ethylene signaling, also negatively regulate PAMP-triggered immunity. Plants lacking EIN3 and EIL1 display enhanced PAMP defenses and heightened resistance to Pseudomonas syringae bacteria. Conversely, plants overaccumulating EIN3 are compromised in PAMP defenses and exhibit enhanced disease susceptibility to Pseudomonas syringae. Microarray analysis revealed that EIN3 and EIL1 negatively control PAMP response genes. Further analyses indicated that SALICYLIC ACID INDUCTION DEFICIENT2 (SID2), which encodes isochorismate synthase required for pathogen-induced biosynthesis of salicylic acid (SA), is a key target of EIN3 and EIL1. Consistent with this, the ein3-1 eil1-1 double mutant constitutively accumulates SA in the absence of pathogen attack, and a mutation in SID2 restores normal susceptibility in the ein3 eil1 double mutant. EIN3 can specifically bind SID2 promoter sequence in vitro and in vivo. Taken together, our data provide evidence that EIN3/EIL1 directly target SID2 to downregulate PAMP defenses.; Biochemistry & Molecular Biology; Plant Sciences; Cell Biology; SCI(E); 50; ARTICLE; 8; 2527-2540; 21
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/396856]
专题	生命科学学院
推荐引用方式 GB/T 7714	Chen, Huamin,Xue, Li,Chintamanani, Satya,et al. ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate Immunity in Arabidopsis[J]. plant cell,2009.
APA	Chen, Huamin.,Xue, Li.,Chintamanani, Satya.,Germain, Hugo.,Lin, Huiqiong.,...&Zhou, Jian-Min.(2009).ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate Immunity in Arabidopsis.plant cell.
MLA	Chen, Huamin,et al."ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate Immunity in Arabidopsis".plant cell (2009).