GENERATION OF EARLY AFTERDEPOLARIZATION IN MOUSE VENTRICULAR FIBERS AT   LONG CYCLE LENGTH

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	GENERATION OF EARLY AFTERDEPOLARIZATION IN MOUSE VENTRICULAR FIBERS AT LONG CYCLE LENGTH
	HAO, S ; LIU, TF
刊名	methods and findings in experimental and clinical pharmacology
	1993
关键词	EARLY AFTERDEPOLARIZATION DURATION OF ACTION POTENTIAL VENTRICULAR FIBERS TRIGGERED ACTIVITY MOUSE HEART ARRHYTHMOGENESIS TRIGGERED ACTIVITY CARDIAC TISSUE ATRIAL FIBERS K+ NIFEDIPINE
英文摘要	Early after depolarization (EAD) was studied in ventricular fibers of mouse heart. EAD could be occasionally induced wider long cycle length of superfusion with Tyrode's solution (containing 3.0 or 5.0 mM KCl) at long cycle length. Three types of EAD were found: a second plateau with a prominence, a single triggered burst and a train of triggered bursts. Take-off potential of the first triggered burst or of the prominence varied from -40 to -60 mV. The triggerd bursts in the third type often stopped at -35 to -45 mV level forming a very long second plateau before it completely repolarized. Changing abruptly from a long cycle length to a short one lead to a transient EAD induction. It is suggested that EAD in ventricular fiber in mouse heart shared the characteristics of that in atrial fibers, although it was very difficult to induce and was not very reproducible.; Pharmacology & Pharmacy; SCI(E); PubMed; 1; ARTICLE; 1; 15-21; 15
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/348018]
专题	生命科学学院
推荐引用方式 GB/T 7714	HAO, S,LIU, TF. GENERATION OF EARLY AFTERDEPOLARIZATION IN MOUSE VENTRICULAR FIBERS AT LONG CYCLE LENGTH[J]. methods and findings in experimental and clinical pharmacology,1993.
APA	HAO, S,&LIU, TF.(1993).GENERATION OF EARLY AFTERDEPOLARIZATION IN MOUSE VENTRICULAR FIBERS AT LONG CYCLE LENGTH.methods and findings in experimental and clinical pharmacology.
MLA	HAO, S,et al."GENERATION OF EARLY AFTERDEPOLARIZATION IN MOUSE VENTRICULAR FIBERS AT LONG CYCLE LENGTH".methods and findings in experimental and clinical pharmacology (1993).