Comparison of lucifer yellow leakage and cell-to-cell transfer following   intracellular injection in normal and antisense novikoff cells under   treatment with low extracellular Ca2+

CORC > 北京大学 > 生命科学学院

	Comparison of lucifer yellow leakage and cell-to-cell transfer following intracellular injection in normal and antisense novikoff cells under treatment with low extracellular Ca2+
	Liu, TF ; Li, HY ; Atkinson, MM ; Johnson, RG
刊名	methods and findings in experimental and clinical pharmacology
	1996
关键词	Novikoff cells antisense cells Lucifer Yellow gap junction hemi-channel dye leakage cell-to-cell dye transfer GAP-JUNCTION CHANNELS MEMBRANE
英文摘要	Single and paired control Novikoff and connexin 43 antisense-transfected Novikoff cells (antisense cells) were used to investigate the differences of intercellular dye transfer and leakage between these two types of cells. Lucifer Yellow was injected into cells by iontophoresis. There was no dye leakage in single cells of both types in Swims solution. The dye transfer from injected cell to recipient cell in the normal solution was different in the two types of cell pairs. The transfer was significantly suppressed in antisense cells; 46/84 cases were blocked vs. 1/84 in Novikoff cell pairs. Under EGTA treatment, the dye leakage in single antisense cells was suppressed showing an increase in the very slow rate of leakage (16/40 vs. 6/40), and the mean rate of leakage was also significantly low This suggests that dye transfer and leakage are suppressed in antisense cells and demonstrates that connexin 43 plays ail important part both in dye transfer in paired cells and dye leakage in single cells.; Pharmacology & Pharmacy; SCI(E); PubMed; 7; ARTICLE; 8; 493-497; 18
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/347968]
专题	生命科学学院
推荐引用方式 GB/T 7714	Liu, TF,Li, HY,Atkinson, MM,et al. Comparison of lucifer yellow leakage and cell-to-cell transfer following intracellular injection in normal and antisense novikoff cells under treatment with low extracellular Ca2+[J]. methods and findings in experimental and clinical pharmacology,1996.
APA	Liu, TF,Li, HY,Atkinson, MM,&Johnson, RG.(1996).Comparison of lucifer yellow leakage and cell-to-cell transfer following intracellular injection in normal and antisense novikoff cells under treatment with low extracellular Ca2+.methods and findings in experimental and clinical pharmacology.
MLA	Liu, TF,et al."Comparison of lucifer yellow leakage and cell-to-cell transfer following intracellular injection in normal and antisense novikoff cells under treatment with low extracellular Ca2+".methods and findings in experimental and clinical pharmacology (1996).