Duplication and adaptive evolution of the chalcone synthase genes of   dendranthema (Asteraceae)

CORC > 北京大学 > 生命科学学院

	Duplication and adaptive evolution of the chalcone synthase genes of dendranthema (Asteraceae)
	Yang, J ; Huang, JX ; Gu, HY ; Zhong, Y ; Yang, ZH
刊名	分子生物学与进化
	2002
关键词	duplication adaptive evolution chalcone synthase gene family Dendranthema CODON-SUBSTITUTION MODELS MOLECULAR EVOLUTION NUCLEOTIDE SUBSTITUTIONS MAXIMUM-LIKELIHOOD PHYLOGENETIC ANALYSIS MULTIGENE FAMILY PLANT DEFENSE DNA-SEQUENCES NUCLEAR GENES SELECTION
英文摘要	Chalcone synthase (CHS) is a key enzyme in the biosynthesis of flavonoids, which are important for the pigmentation of flowers and act as attractants to the pollinators. Genes encoding CHS constitute a multigene family in which the copy number varies among plant species and functional divergence appears to have occurred repeatedly. Plants of the Dendranthema genus have white, yellow, and pink flowers, exhibiting considerable variation in flower color. In this article, 18 CHS genes from six Dendranthema species were sequenced. Two of them were found to be pseudogenes. The functional Dendranthema CHS genes formed three well-supported subfamilies: SF1, SF2, and SF3. The inferred phylogeny of the CHS genes of Dendranthema and Gerbera suggests that those genes originated as a result of duplications before divergence of these two genera, and the function of Dendranthema CHS genes have diverged in a similar fashion to the Gerbera CHS genes; i.e., the genes of SF1 and SF3 code for typical CHS enzymes expressed during different stages of development, whereas the genes of SF2 code for another enzyme that is different from CHS in substrate specificity and reaction. Relative rate tests revealed that the Dendranthema CHS genes significantly deviated from clocklike evolution at nonsynonymous sites. Maximum likelihood analysis showed that the nonsynonymous-synonymous (omega = d(N)/d(S)) rate ratio for the lineage ancestral to SF2 was much higher than for other lineages, with some sites having a ratio well above one. Positive selective pressure appears to have driven the divergence of SF2 from SF1 and SF3.; Biochemistry & Molecular Biology; Evolutionary Biology; Genetics & Heredity; SCI(E); PubMed; 27; ARTICLE; 10; 1752-1759; 19
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/347286]
专题	生命科学学院
推荐引用方式 GB/T 7714	Yang, J,Huang, JX,Gu, HY,et al. Duplication and adaptive evolution of the chalcone synthase genes of dendranthema (Asteraceae)[J]. 分子生物学与进化,2002.
APA	Yang, J,Huang, JX,Gu, HY,Zhong, Y,&Yang, ZH.(2002).Duplication and adaptive evolution of the chalcone synthase genes of dendranthema (Asteraceae).分子生物学与进化.
MLA	Yang, J,et al."Duplication and adaptive evolution of the chalcone synthase genes of dendranthema (Asteraceae)".分子生物学与进化 (2002).