Studies on the epitope of neuronal growth inhibitory factor (GIF) with using of the specific antibody | |
Pang, LY ; Ru, BG | |
刊名 | journal of biochemistry and molecular biology
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2005 | |
关键词 | antibody domain enzyme-linked immunosorbent assay (ELISA) epitope human neuronal growth inhibitory factor (GIF) ALZHEIMERS-DISEASE BRAIN MOLECULAR-CLONING BIOLOGICAL-ACTIVITY DOWN-REGULATION FACTOR CDNA EXPRESSION PROTEIN GENE |
英文摘要 | Human neuronal growth inhibitory factor (GIF), a metalloprotein classified as metallothionein-3, is specifically expressed in mammal central nervous system (CNS). In these Studies the specific antibody to human GIF was prepared and used to search the epitope of human GIF by enzyme-linked immunosorbent assay (ELISA) and sequence comparison. The result of ELISA showed the epitope of human GIF may locate on a octapepticle (EAAEAEAE) in the alpha-domain of human GIF, and the result of nerve cell culture indicated that the biological activity of GIF may be affected by the specific antibody.; Biochemistry & Molecular Biology; SCI(E); PubMed; 2; ARTICLE; 6; 646-649; 38 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/346175] ![]() |
专题 | 生命科学学院 |
推荐引用方式 GB/T 7714 | Pang, LY,Ru, BG. Studies on the epitope of neuronal growth inhibitory factor (GIF) with using of the specific antibody[J]. journal of biochemistry and molecular biology,2005. |
APA | Pang, LY,&Ru, BG.(2005).Studies on the epitope of neuronal growth inhibitory factor (GIF) with using of the specific antibody.journal of biochemistry and molecular biology. |
MLA | Pang, LY,et al."Studies on the epitope of neuronal growth inhibitory factor (GIF) with using of the specific antibody".journal of biochemistry and molecular biology (2005). |
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