Arabidopsis Putative Deacetylase AtSRT2 Regulates Basal Defense by   Suppressing PAD4, EDS5 and SID2 Expression

doi:10.1093/pcp/pcq087

CORC > 北京大学 > 生命科学学院

	Arabidopsis Putative Deacetylase AtSRT2 Regulates Basal Defense by Suppressing PAD4, EDS5 and SID2 Expression
	Wang, Chunzheng ; Gao, Feng ; Wu, Jianguo ; Dai, Jianli ; Wei, Chunhong ; Li, Yi
刊名	plant and cell physiology
	2010
关键词	AtSRT2 Basal defense EDS5 PAD4 PstDC3000 SID2 SYSTEMIC ACQUIRED-RESISTANCE SALICYLIC-ACID GENE-EXPRESSION HISTONE ACETYLATION PLANT DEFENSE PROTEIN DEACETYLASES DISEASE RESISTANCE SIR2 FAMILY THALIANA SIRTUINS
DOI	10.1093/pcp/pcq087
英文摘要	The silent information regulator protein (Sir2) and its homologs are NAD(+)-dependent deacetylase enzymes that play important roles in a variety of physiological processes. However, the functions of the Sir2 family in plants are poorly understood. Here, we report that Arabidopsis AtSRT2, a homolog of yeast Sir2, negatively regulates plant basal defense against the pathogen Pseudomonas syringae pv. tomato DC3000 (PstDC3000). In response to PstDC3000 infection, the expression of AtSRT2 was down-regulated in a salicylic acid (SA)-independent manner. In addition, knock-out of AtSRT2 (srt2) enhanced resistance against PstDC3000 and increased expression of pathogenesis-related gene 1 (PR1). Conversely, overexpression of AtSRT2 resulted in hypersusceptibility to PstDC3000 and impaired PR1 induction. Consistent with this phenotype, expression of PAD4, EDS5 and SID2, three essential genes in the SA biosynthesis pathway, were increased in the srt2 mutant and decreased in AtSRT2-overexpressing plants. Taken together, these results demonstrate that AtSRT2 is a negative regulator of basal defense, possibly by suppressing SA biosynthesis.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000280918700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Plant Sciences; Cell Biology; SCI(E); 42; ARTICLE; 8; 1291-1299; 51
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/320241]
专题	生命科学学院
推荐引用方式 GB/T 7714	Wang, Chunzheng,Gao, Feng,Wu, Jianguo,et al. Arabidopsis Putative Deacetylase AtSRT2 Regulates Basal Defense by Suppressing PAD4, EDS5 and SID2 Expression[J]. plant and cell physiology,2010.
APA	Wang, Chunzheng,Gao, Feng,Wu, Jianguo,Dai, Jianli,Wei, Chunhong,&Li, Yi.(2010).Arabidopsis Putative Deacetylase AtSRT2 Regulates Basal Defense by Suppressing PAD4, EDS5 and SID2 Expression.plant and cell physiology.
MLA	Wang, Chunzheng,et al."Arabidopsis Putative Deacetylase AtSRT2 Regulates Basal Defense by Suppressing PAD4, EDS5 and SID2 Expression".plant and cell physiology (2010).