Identification of An E3 Ubiquitin Ligase Required for IRF3 K63-ubiquitination and Activation | |
Jiang ZF(蒋争凡) | |
2012 | |
关键词 | Ubiquitin Transcription translocation tightly Activation nucleus residues regulate serine ubiquitin |
英文摘要 | Virus infection induces the production of type I IFNs.Transcription factor IFN regulatory factor 3(IRF3) plays an essential role and is tightly regulated in this process.It was demonstrated that TBK1 phosphorylates IRF3 at key serine residues,leading to its dimerization and translocation to the n...; 0 |
语种 | 英语 |
内容类型 | 其他 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/320216] |
专题 | 生命科学学院 |
推荐引用方式 GB/T 7714 | Jiang ZF. Identification of An E3 Ubiquitin Ligase Required for IRF3 K63-ubiquitination and Activation. 2012-01-01. |
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