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Identification of An E3 Ubiquitin Ligase Required for IRF3 K63-ubiquitination and Activation
Jiang ZF(蒋争凡)
2012
关键词Ubiquitin Transcription translocation tightly Activation nucleus residues regulate serine ubiquitin
英文摘要Virus infection induces the production of type I IFNs.Transcription factor IFN regulatory factor 3(IRF3) plays an essential role and is tightly regulated in this process.It was demonstrated that TBK1 phosphorylates IRF3 at key serine residues,leading to its dimerization and translocation to the n...; 0
语种英语
内容类型其他
源URL[http://ir.pku.edu.cn/handle/20.500.11897/320216]  
专题生命科学学院
推荐引用方式
GB/T 7714
Jiang ZF. Identification of An E3 Ubiquitin Ligase Required for IRF3 K63-ubiquitination and Activation. 2012-01-01.
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