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Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray
Bi, Qun ; Tan, Taochao ; Xiang, Xi ; Lu, Aiping ; Zhu, Shenggeng
2010
关键词breast tumor high-throughput screening microarray phase display related antigen serological identification CELLS CARCINOMA CLONES TARGET
DOI10.1515/BC.2010.075
英文摘要High-throughput molecular profiling techniques are helpful in the diagnosis of multifactorial disease. In this study, a cDNA-phage-displayed protein microarray using phage particles spotted directly onto it as sensors was used to detect related antigens in breast tumor sera. cDNA sequences from 17 positive clones were determined, which included some sequences encoding known breast cancer-related antigens and proteins related to other diseases, as well as proteins with unknown functions. Our results not only provide some useful information for breast cancer research, but also suggest that the strategy used here would be efficient to search for disease-related proteins and other functional target proteins.; Biochemistry & Molecular Biology; SCI(E); PubMed; 1; ARTICLE; 7; 831-835; 391
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/319975]  
专题生命科学学院
推荐引用方式
GB/T 7714
Bi, Qun,Tan, Taochao,Xiang, Xi,et al. Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray[J],2010.
APA Bi, Qun,Tan, Taochao,Xiang, Xi,Lu, Aiping,&Zhu, Shenggeng.(2010).Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray..
MLA Bi, Qun,et al."Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray".(2010).
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