Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray | |
Bi, Qun ; Tan, Taochao ; Xiang, Xi ; Lu, Aiping ; Zhu, Shenggeng | |
2010 | |
关键词 | breast tumor high-throughput screening microarray phase display related antigen serological identification CELLS CARCINOMA CLONES TARGET |
DOI | 10.1515/BC.2010.075 |
英文摘要 | High-throughput molecular profiling techniques are helpful in the diagnosis of multifactorial disease. In this study, a cDNA-phage-displayed protein microarray using phage particles spotted directly onto it as sensors was used to detect related antigens in breast tumor sera. cDNA sequences from 17 positive clones were determined, which included some sequences encoding known breast cancer-related antigens and proteins related to other diseases, as well as proteins with unknown functions. Our results not only provide some useful information for breast cancer research, but also suggest that the strategy used here would be efficient to search for disease-related proteins and other functional target proteins.; Biochemistry & Molecular Biology; SCI(E); PubMed; 1; ARTICLE; 7; 831-835; 391 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/319975] |
专题 | 生命科学学院 |
推荐引用方式 GB/T 7714 | Bi, Qun,Tan, Taochao,Xiang, Xi,et al. Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray[J],2010. |
APA | Bi, Qun,Tan, Taochao,Xiang, Xi,Lu, Aiping,&Zhu, Shenggeng.(2010).Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray.. |
MLA | Bi, Qun,et al."Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray".(2010). |
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