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	The role of CopG mediated DNA bending on the regulation of the sigma(54)-dependent promoters in E-coli
	Chen, YC ; Yang, EC ; Liu, ZF ; Tian, ZX ; Wang, YP
刊名	科学通报 英文版
	2006
关键词	sigma(54)-dependent promoter DNA bending CopG helix phase KLEBSIELLA-PNEUMONIAE PLASMID PLS1 TRANSCRIPTION PROTEIN COMPLEXES REPRESSOR ACTIVATOR REPA RNA PRODUCTS
DOI	10.1007/s11434-006-0934-6
英文摘要	In order to investigate the role of DNA bending on the regulation of (sigma(54)-dependent promoters, we introduced the CopG binding site between the enhancer-like element and the core promoter of glnAp2, nifLp and glnHp2, without changing the distance in between. The expression activities of these homologous promoters were either activated or repressed by the CopG-induced DNA bending in E coli. In this case, similar regulatory pattern (either activated or repressed) could be observed, when the bending centers from CopG are in integral DNA helixes interval, while opposite regulatory pattern could be observed, when the bending centers from CopG are in integral plus a half DNA helixes interval. These results suggested that CopG-induced DNA bending can exert regulatory effects on the transcription of sigma(54)-dependent promoters probably by altering the relative DNA helix phase of 54 RNA polymerase and NtrC.; Multidisciplinary Sciences; SCI(E); 中文核心期刊要目总览(PKU); 中国科学引文数据库(CSCD); 0; 8; 934-940; 51
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/252512]
专题	生命科学学院
推荐引用方式 GB/T 7714	Chen, YC,Yang, EC,Liu, ZF,et al. The role of CopG mediated DNA bending on the regulation of the sigma(54)-dependent promoters in E-coli[J]. 科学通报 英文版,2006.
APA	Chen, YC,Yang, EC,Liu, ZF,Tian, ZX,&Wang, YP.(2006).The role of CopG mediated DNA bending on the regulation of the sigma(54)-dependent promoters in E-coli.科学通报 英文版.
MLA	Chen, YC,et al."The role of CopG mediated DNA bending on the regulation of the sigma(54)-dependent promoters in E-coli".科学通报 英文版 (2006).

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