Evidence that natural selection is the primary cause of the   guanine-cytosine content variation in rice genes

doi:10.1111/j.1672-9072.2007.00532.x

CORC > 北京大学 > 生命科学学院

	Evidence that natural selection is the primary cause of the guanine-cytosine content variation in rice genes
	Shi, Xiaoli ; Wang, Xiyin ; Li, Zhe ; Zhu, Qihui ; Yang, Ji ; Ge, Song ; Luo, Jingchu
刊名	journal of integrative plant biology
	2007
关键词	guanine-cytosine content mutation bias natural selection paralogs synonymous substitution rate two gene classes CODON USAGE BIAS NONSYNONYMOUS SUBSTITUTION RATES SYNONYMOUS SUBSTITUTION NUCLEOTIDE SUBSTITUTION MAXIMUM-LIKELIHOOD GENOME EVOLUTION MAMMALIAN GENOME GC CONTENT DNA DROSOPHILA
DOI	10.1111/j.1672-9072.2007.00532.x
英文摘要	Cereal genes are classified into two distinct classes according to the guanine-cytosine (GC) content at the third codon sites (GC(3)). Natural selection and mutation bias have been proposed to affect the GC content. However, there has been controversy about the cause of GC variation. Here, we characterized the GC content of 1092 paralogs and other single-copy genes in the duplicated chromosomal regions of the rice genome (ssp. indica) and classified the paralogs into GC(3)-rich and GC(3)-poor groups. By referring to out-group sequences from Arabidopsis and maize, we confirmed that the average synonymous substitution rate of the GC3-rich genes is significantly lower than that of the GC3-poor genes. Furthermore, we explored the other possible factors corresponding to the GC variation including the length of coding sequences, the number of exons in each gene, the number of genes in each family, the location of genes on chromosomes and the protein functions. Consequently, we propose that natural selection rather than mutation bias was the primary cause of the GC variation.; Biochemistry & Molecular Biology; Plant Sciences; SCI(E); 中国科技核心期刊(ISTIC); 中国科学引文数据库(CSCD); 0; ARTICLE; 9; 1393-1399; 49
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/249784]
专题	生命科学学院
推荐引用方式 GB/T 7714	Shi, Xiaoli,Wang, Xiyin,Li, Zhe,et al. Evidence that natural selection is the primary cause of the guanine-cytosine content variation in rice genes[J]. journal of integrative plant biology,2007.
APA	Shi, Xiaoli.,Wang, Xiyin.,Li, Zhe.,Zhu, Qihui.,Yang, Ji.,...&Luo, Jingchu.(2007).Evidence that natural selection is the primary cause of the guanine-cytosine content variation in rice genes.journal of integrative plant biology.
MLA	Shi, Xiaoli,et al."Evidence that natural selection is the primary cause of the guanine-cytosine content variation in rice genes".journal of integrative plant biology (2007).