Identification of Pns6, a putative movement protein of RRSV, as a   silencing suppressor

doi:10.1186/1743-422X-7-335

CORC > 北京大学 > 生命科学学院

	Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor
	Wu, Jianguo ; Du, Zhenguo ; Wang, Chunzheng ; Cai, Lijun ; Hu, Meiqun ; Lin, Qiying ; Wu, Zujian ; Li, Yi ; Xie, Lianhui
刊名	virology journal
	2010
关键词	RICE-RAGGED-STUNT TO-CELL MOVEMENT LONG-DISTANCE MOVEMENT VIRAL SUPPRESSORS ANTIVIRAL IMMUNITY RNA-BINDING VIRUS GENOME ORYZAVIRUS PLANTS
DOI	10.1186/1743-422X-7-335
英文摘要	RNA silencing is a potent antiviral response in plants. As a counterdefense, most plant and some animal viruses encode RNA silencing suppressors. In this study, we showed that Pns6, a putative movement protein of Rice ragged stunt virus (RRSV), exhibited silencing suppressor activity in coinfiltration assays with the reporter green fluorescent protein (GFP) in transgenic Nicotiana benthamiana line 16c. Pns6 of RRSV suppressed local silencing induced by sense RNA but had no effect on that induced by dsRNA. Deletion of a region involved in RNA binding abolished the silencing suppressor activity of Pns6. Further, expression of Pns6 enhanced Potato virus x pathogenicity in N. benthamiana. Collectively, these results suggested that RRSV Pns6 functions as a virus suppressor of RNA silencing that targets an upstream step of the dsRNA formation in the RNA silencing pathway. This is the first silencing suppressor to be identified from the genus Oryzavirus.; Virology; SCI(E); 6; ARTICLE; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/241676]
专题	生命科学学院
推荐引用方式 GB/T 7714	Wu, Jianguo,Du, Zhenguo,Wang, Chunzheng,et al. Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor[J]. virology journal,2010.
APA	Wu, Jianguo.,Du, Zhenguo.,Wang, Chunzheng.,Cai, Lijun.,Hu, Meiqun.,...&Xie, Lianhui.(2010).Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor.virology journal.
MLA	Wu, Jianguo,et al."Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor".virology journal (2010).