Inhibitory effects of calcitonin gene-related peptide on long-term   potentiation induced in hippocampal slices of rats

doi:10.1016/j.neulet.2011.02.036

CORC > 北京大学 > 生命科学学院

	Inhibitory effects of calcitonin gene-related peptide on long-term potentiation induced in hippocampal slices of rats
	Liu, Xiao-Dong ; Zhang, Jian-Jun ; Wang, Yao ; Yu, Long-Chuan
刊名	神经科学快报
	2011
关键词	Calcitonin gene-related peptide (CGRP) CGRP 8-37 Hippocampus Learning and memory Long term potentiation (LTP) MOSSY CELLS IN-VIVO VASODILATOR CGRP MEMORY NEUROPEPTIDE RECEPTOR NEURONS ADRENOMEDULLIN STIMULATION
DOI	10.1016/j.neulet.2011.02.036
英文摘要	It is well known that hippocampus plays important roles in learning and memory. Both calcitonin generelated peptide (CGRP) and CGRP receptors are found in hippocampus. In the present study we explored the influence of CGRP on long term potentiation (LIP) in hippocampal Schaffer collateral-CA1. Our results demonstrated that CGRP inhibited the LIP induced by high frequency stimulation (HES) in hippocampal CA1 neurons in rat brain slices. The inhibitory effect was blocked by CGRP receptor-1 antagonist CGRP 8-37. The results indicate that both CGRP and CGRP receptor 1 are involved in the modulation process of LTP in hippocampus of rats. (C) 2011 Elsevier Ireland Ltd. All rights reserved.; Neurosciences; SCI(E); PubMed; 2; ARTICLE; 1; 10-13; 494
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/195041]
专题	生命科学学院
推荐引用方式 GB/T 7714	Liu, Xiao-Dong,Zhang, Jian-Jun,Wang, Yao,et al. Inhibitory effects of calcitonin gene-related peptide on long-term potentiation induced in hippocampal slices of rats[J]. 神经科学快报,2011.
APA	Liu, Xiao-Dong,Zhang, Jian-Jun,Wang, Yao,&Yu, Long-Chuan.(2011).Inhibitory effects of calcitonin gene-related peptide on long-term potentiation induced in hippocampal slices of rats.神经科学快报.
MLA	Liu, Xiao-Dong,et al."Inhibitory effects of calcitonin gene-related peptide on long-term potentiation induced in hippocampal slices of rats".神经科学快报 (2011).