Arabidopsis noncoding RNA mediates control of photomorphogenesis by red   light

doi:10.1073/pnas.1409457111

CORC > 北京大学 > 生命科学学院

	Arabidopsis noncoding RNA mediates control of photomorphogenesis by red light
	Wang, Yuqiu ; Fan, Xiuduo ; Lin, Fang ; He, Guangming ; Terzaghi, William ; Zhu, Danmeng ; Deng, Xing Wang
刊名	proceedings of the national academy of sciences of the united states of america
	2014
关键词	light signaling transcriptional regulation PLANT DEVELOPMENT TRANSCRIPTIONAL NETWORKS SIGNAL-TRANSDUCTION MALE-STERILITY MECHANISMS GENES EXPRESSION COMPONENTS SEQUENCE TARGET
DOI	10.1073/pnas.1409457111
英文摘要	Seedling photomorphogenesis is a sophisticated developmental process that is controlled by both the transcriptional and post-transcriptional regulation of gene expression. Here, we identify an Arabidopsis noncoding RNA, designated HIDDEN TREASURE 1 (HID1), as a factor promoting photomorphogenesis in continuous red light (cR). We show that HID1 acts through PHYTOCHROME-INTERACTING FACTOR 3 (PIF3), which encodes a basic helix-loop-helix transcription factor known to be a key repressor of photomorphogenesis. Knockdown of HID1 in hid1 mutants leads to a significant increase in the expression of PIF3, which in turn drives the development of elongated hypocotyls in cR. We identified two major stem-loops in HID1 that are essential for its modulation of hypocotyl growth in cR-grown seedlings. Furthermore, our data reveal that HID1 is assembled into large nuclear protein-RNA complex(es) and that it associates with the chromatin of the first intron of PIF3 to repress its transcription. Strikingly, phylogenetic analysis reveals that many land plants have conserved homologs of HID1 and that its rice homolog can rescue the mutant phenotype when expressed in Arabidopsis hid1 mutants. We thus concluded that HID1 is a previously uncharacterized noncoding RNA whose function represents another layer of regulation in the precise control of seedling photomorphogenesis.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000338985700073&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Multidisciplinary Sciences; SCI(E); PubMed; 17; ARTICLE; zhudanmeng@pku.edu.cn; xingwang.deng@yale.edu; 28; 10359-10364; 111
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/162443]
专题	生命科学学院
推荐引用方式 GB/T 7714	Wang, Yuqiu,Fan, Xiuduo,Lin, Fang,et al. Arabidopsis noncoding RNA mediates control of photomorphogenesis by red light[J]. proceedings of the national academy of sciences of the united states of america,2014.
APA	Wang, Yuqiu.,Fan, Xiuduo.,Lin, Fang.,He, Guangming.,Terzaghi, William.,...&Deng, Xing Wang.(2014).Arabidopsis noncoding RNA mediates control of photomorphogenesis by red light.proceedings of the national academy of sciences of the united states of america.
MLA	Wang, Yuqiu,et al."Arabidopsis noncoding RNA mediates control of photomorphogenesis by red light".proceedings of the national academy of sciences of the united states of america (2014).