Geminal difunctionalization of alpha-diazo arylmethylphosphonates:   synthesis of fluorinated phosphonates

doi:10.1039/c6ob01858k

CORC > 北京大学 > 化学与分子工程学院

	Geminal difunctionalization of alpha-diazo arylmethylphosphonates: synthesis of fluorinated phosphonates
	Zhou, Yujing ; Zhang, Yan ; Wang, Jianbo
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2016
关键词	DIMETHYLPHOSPHONO-SUBSTITUTED DIAZOALKANES CARBOXYLIC-ACID DERIVATIVES TYROSINE-PHOSPHATASE 1B ARYL BORONIC ACIDS ELECTROPHILIC FLUORINATION SH2 DOMAIN INHIBITOR HALIDES HYDROFLUORINATION INSERTION
DOI	10.1039/c6ob01858k
英文摘要	A general approach towards diverse fluorinated phosphonates via geminal difunctionalization reactions of a-diazo arylmethylphosphonates is described. The diazo functionality (RR'C=N-2) is successfully converted to RR'CF2, RR'CHF, RR'CFBr or RR'CFNR ''(2) groups by employing different fluorination reagents. A variety of fluorinated organophosphorus compounds were readily accessed in good to excellent yields from a common type of precursor.; National Basic Research Program of China (973 Program) [2015CB856600]; National Natural Science Foundation of China [21472004, 21332002]; SCI(E); PubMed; ARTICLE; wangjb@pku.edu.cn; 44; 10444-10453; 14
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/457355]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhou, Yujing,Zhang, Yan,Wang, Jianbo. Geminal difunctionalization of alpha-diazo arylmethylphosphonates: synthesis of fluorinated phosphonates[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2016.
APA	Zhou, Yujing,Zhang, Yan,&Wang, Jianbo.(2016).Geminal difunctionalization of alpha-diazo arylmethylphosphonates: synthesis of fluorinated phosphonates.ORGANIC & BIOMOLECULAR CHEMISTRY.
MLA	Zhou, Yujing,et al."Geminal difunctionalization of alpha-diazo arylmethylphosphonates: synthesis of fluorinated phosphonates".ORGANIC & BIOMOLECULAR CHEMISTRY (2016).