Recent advances in lipidomics for disease research

doi:10.1002/jssc.201500899

CORC > 北京大学 > 化学与分子工程学院

	Recent advances in lipidomics for disease research
	Yang, Li ; Li, Min ; Shan, Yabing ; Shen, Sensen ; Bai, Yu ; Liu, Huwei
刊名	JOURNAL OF SEPARATION SCIENCE
	2016
关键词	Biomarkers Clinical diagnosis Lipidomics Metabolism DESORPTION ELECTROSPRAY-IONIZATION 2-DIMENSIONAL GAS-CHROMATOGRAPHY IMAGING MASS-SPECTROMETRY PERITONEAL-DIALYSIS PATIENTS FATTY-ACID SYNTHASE LC-QTOF-MS ALZHEIMERS-DISEASE SHOTGUN LIPIDOMICS BREAST-CANCER HUMAN PLASMA
DOI	10.1002/jssc.201500899
英文摘要	Lipidomics is an important branch of metabolomics, which aims at the detailed analysis of lipid species and their multiple roles in the living system. In recent years, the development of various analytical methods for effective identification and characterization of lipids has greatly promoted the process of lipidomics. Meanwhile, as many diseases demonstrate a remarkable alteration in lipid profiles compared with that of healthy people, lipidomics has been extensively introduced to disease research. The comprehensive lipid profiling provides a chance to discover novel biomarkers for specific disease. In addition, it plays a crucial role in the study of lipid metabolism, which could illuminate the pathogenesis of diseases. In this review, after brief discussion of analytical methods for lipidomics in clinical research, we focus on the recent advances of lipidomics related to four types of diseases, including cancer, atherosclerosis, diabetes mellitus, and Alzheimer's disease.; National Natural Science Foundation of China [21175005, 21275012l]; Ministry of Science and Technology of China [2012YQ090194-9, 2013YQ510391]; SCI(E); EI; REVIEW; hwliu@pku.edu.cn; 1; 38-50; 39
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/438005]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Yang, Li,Li, Min,Shan, Yabing,et al. Recent advances in lipidomics for disease research[J]. JOURNAL OF SEPARATION SCIENCE,2016.
APA	Yang, Li,Li, Min,Shan, Yabing,Shen, Sensen,Bai, Yu,&Liu, Huwei.(2016).Recent advances in lipidomics for disease research.JOURNAL OF SEPARATION SCIENCE.
MLA	Yang, Li,et al."Recent advances in lipidomics for disease research".JOURNAL OF SEPARATION SCIENCE (2016).