Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of   alpha-Diazo Phosphonates with Benzyl or Allyl Halides

doi:10.1021/acs.joc.5b00629

CORC > 北京大学 > 化学与分子工程学院

	Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of alpha-Diazo Phosphonates with Benzyl or Allyl Halides
	Zhou, Yujing ; Ye, Fei ; Wang, Xi ; Xu, Shuai ; Zhang, Yan ; Wang, Jianbo
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2015
关键词	SUBSTITUTED ALPHA,BETA-UNSATURATED PHOSPHONATES DYNAMIC KINETIC RESOLUTION ASYMMETRIC HYDROGENATION ENANTIOSELECTIVE SYNTHESIS DIAZOCARBONYL COMPOUNDS OXIDATIVE ADDITION N-TOSYLHYDRAZONES CROSS-METATHESIS ALKYNES EFFICIENT
DOI	10.1021/acs.joc.5b00629
英文摘要	An efficient method for the synthesis of organophosphonates through palladium-catalyzed coupling of a-diazo phosphonates with benzyl or allyl halides has been developed. Trisubstituted alkenylphosphonates bearing versatile functional groups can be easily accessed in good yields and with excellent stereoselectivity through this method. Moreover, with similar strategy a-substituted vinylphosphonates can also be attained by the palladium-catalyzed coupling reaction of N-tosylhydrazones and aryl bromides. Migratory insertion of palladium carbene is proposed as the key step in this reaction.; National Basic Research Program of China (973 Program) [2012CB821600]; National Natural Science Foundation of China [21472004, 21332002]; SCI(E); EI; PubMed; ARTICLE; wangjb@pku.edu.cn; 12; 6109-6118; 80
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/419190]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhou, Yujing,Ye, Fei,Wang, Xi,et al. Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of alpha-Diazo Phosphonates with Benzyl or Allyl Halides[J]. JOURNAL OF ORGANIC CHEMISTRY,2015.
APA	Zhou, Yujing,Ye, Fei,Wang, Xi,Xu, Shuai,Zhang, Yan,&Wang, Jianbo.(2015).Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of alpha-Diazo Phosphonates with Benzyl or Allyl Halides.JOURNAL OF ORGANIC CHEMISTRY.
MLA	Zhou, Yujing,et al."Synthesis of Alkenylphosphonates through Palladium-Catalyzed Coupling of alpha-Diazo Phosphonates with Benzyl or Allyl Halides".JOURNAL OF ORGANIC CHEMISTRY (2015).