Rhodium(I)-Catalyzed Sequential C(sp)C(sp(3)) and C(sp(3))C(sp(3)) Bond Formation through Migratory Carbene Insertion | |
Xia, Ying ; Feng, Sheng ; Liu, Zhen ; Zhang, Yan ; Wang, Jianbo | |
刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
2015 | |
关键词 | carbenes cross-couplings diazo compounds migratory insertion quaternary carbon center NONACTIVATED ALKYL-HALIDES CROSS-COUPLING REACTIONS ALPHA-DIAZOCARBONYL COMPOUNDS C-C BOND GRIGNARD-REAGENTS SONOGASHIRA REACTIONS N-TOSYLHYDRAZONES C(SP(3))-H BONDS METAL CARBENE ALKYNYLATION |
DOI | 10.1002/anie.201503140 |
英文摘要 | A Rh-I-catalyzed three-component reaction of tert-propargyl alcohol, diazoester, and alkyl halide has been developed. This reaction can be considered as a carbene-involving sequential alkyl and alkynyl coupling, in which C(sp)C(sp(3)) and C(sp(3))C(sp(3)) bonds are built successively on the carbenic carbon atom. The Rh-I-carbene migratory insertion of an alkynyl moiety and subsequent alkylation are proposed to account for the two separate CC bond formations. This reaction provides an efficient and tunable method for the construction of all-carbon quaternary center.; National Basic Research Program of China (973 Program) [2012CB821600]; NSFC [21472004, 21332002]; SCI(E); EI; PubMed; ARTICLE; wangjb@pku.edu.cn; 27; 7891-7894; 54 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/419122] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Xia, Ying,Feng, Sheng,Liu, Zhen,et al. Rhodium(I)-Catalyzed Sequential C(sp)C(sp(3)) and C(sp(3))C(sp(3)) Bond Formation through Migratory Carbene Insertion[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2015. |
APA | Xia, Ying,Feng, Sheng,Liu, Zhen,Zhang, Yan,&Wang, Jianbo.(2015).Rhodium(I)-Catalyzed Sequential C(sp)C(sp(3)) and C(sp(3))C(sp(3)) Bond Formation through Migratory Carbene Insertion.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. |
MLA | Xia, Ying,et al."Rhodium(I)-Catalyzed Sequential C(sp)C(sp(3)) and C(sp(3))C(sp(3)) Bond Formation through Migratory Carbene Insertion".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015). |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论