Preparation of beta-cyclodextrin modified fused silica capillary and its   application in capillary electrophoresis enantiomeric separation

CORC > 北京大学 > 化学与分子工程学院

	Preparation of beta-cyclodextrin modified fused silica capillary and its application in capillary electrophoresis enantiomeric separation
	Zhang, XX ; Hong, F ; Bai, J ; Chang, WB ; Ci, YX
刊名	高等学校化学学报
	1999
关键词	beta-cyclodextrin-immobilized capillary capillary electrophoresis enantiomeric separation PERFORMANCE LIQUID-CHROMATOGRAPHY ZONE ELECTROPHORESIS RETENTION BEHAVIOR CHIRAL SEPARATION ELECTROKINETIC CHROMATOGRAPHY STATIONARY PHASE RESOLUTION COLUMNS
英文摘要	A simple type of chiral selector-immobilized capillaries was prepared and applied to the separation of some enantiomers by capillary electrophoresis(CE) without chiral selective reagents in a buffer solution. beta-Cyclodextrin (CD) was bonded to the inner wall of fused silica capillary with the aid of 3- (2-cyclooxypropoxyl)-propyl-trimethoxy silane or 3-aminopropyltriethoxyl silane as bridge. The synthesis conditions such as reaction temperature, reaction ratios, solvents were optimized. The stability and reproducibility of the CD-modified capillaries were studied under different operation conditions. It is satisfactory to apply the capillary to the chiral separation of d, l-adrenaline and the atracurium besilate diastereoisomers under the optimized conditions.; Chemistry, Multidisciplinary; SCI(E); 中国科学引文数据库(CSCD); 0; ARTICLE; 3; 232-237; 15
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/401565]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhang, XX,Hong, F,Bai, J,et al. Preparation of beta-cyclodextrin modified fused silica capillary and its application in capillary electrophoresis enantiomeric separation[J]. 高等学校化学学报,1999.
APA	Zhang, XX,Hong, F,Bai, J,Chang, WB,&Ci, YX.(1999).Preparation of beta-cyclodextrin modified fused silica capillary and its application in capillary electrophoresis enantiomeric separation.高等学校化学学报.
MLA	Zhang, XX,et al."Preparation of beta-cyclodextrin modified fused silica capillary and its application in capillary electrophoresis enantiomeric separation".高等学校化学学报 (1999).