Highly enantioselective borane reduction of prochiral ketones catalyzed   by C-3-symmetric tripodal beta-hydroxy amides

doi:10.1055/s-2006-94159

CORC > 北京大学 > 化学与分子工程学院

	Highly enantioselective borane reduction of prochiral ketones catalyzed by C-3-symmetric tripodal beta-hydroxy amides
	Fang, Tao ; Xu, Jiaxi ; Du, Da-Ming
刊名	synlett
	2006
关键词	asymmetric reduction borane ketone beta-hydroxyamide C-3 symmetry MEDIATED ASYMMETRIC REDUCTION AROMATIC KETONES CHIRAL OXAZABOROLIDINES AMINO-ALCOHOLS REDUCING AGENT ALDEHYDES NABH4/ME3SICL RECOGNITION SULFONAMIDE
DOI	10.1055/s-2006-94159
英文摘要	The asymmetric borane reduction of prochiral ketones with a series of easily constructed chiral C-3-symmetric tripodal tris(beta-hydroxyamide) ligands was investigated. The borane complex of chiral ligand 1,1',1"-(1,3,5-benzenetricarbonyl)-tris[(2S)-alpha,alpha-diphenl-2-pyrrolidinemethanol] (1h) was found to be an efficient catalyst in asymmetric borane reduction of prochiral ketones and excellent enantioselectivities were obtained with both electron-deficient and electron-rich prochiral ketones (up to 97% ee).; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238732100021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Organic; SCI(E); 24; ARTICLE; 10; 1559-1563
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/398613]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Fang, Tao,Xu, Jiaxi,Du, Da-Ming. Highly enantioselective borane reduction of prochiral ketones catalyzed by C-3-symmetric tripodal beta-hydroxy amides[J]. synlett,2006.
APA	Fang, Tao,Xu, Jiaxi,&Du, Da-Ming.(2006).Highly enantioselective borane reduction of prochiral ketones catalyzed by C-3-symmetric tripodal beta-hydroxy amides.synlett.
MLA	Fang, Tao,et al."Highly enantioselective borane reduction of prochiral ketones catalyzed by C-3-symmetric tripodal beta-hydroxy amides".synlett (2006).