Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy   and Support Vector Machine Classification

doi:10.1155/2013/942427

CORC > 北京大学 > 化学与分子工程学院

	Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification
	Li, Qingbo ; Wang, Wei ; Ling, Xiaofeng ; Wu, Jin Guang
刊名	biomed research international
	2013
关键词	ENDOSCOPIC BIOPSIES CELLS DIAGNOSIS SPECTRA TISSUES
DOI	10.1155/2013/942427
英文摘要	Early diagnosis and early medical treatments are the keys to save the patients' lives and improve the living quality. Fourier transform infrared (FT-IR) spectroscopy can distinguish malignant from normal tissues at the molecular level. In this paper, programs were made with pattern recognition method to classify unknown samples. Spectral data were pretreated by using smoothing and standard normal variate (SNV) methods. Leave-one-out cross validation was used to evaluate the discrimination result of support vector machine (SVM) method. A total of 54 gastric tissue samples were employed in this study, including 24 cases of normal tissue samples and 30 cases of cancerous tissue samples. The discrimination results of SVM method showed the sensitivity with 100%, specificity with 83.3%, and total discrimination accuracy with 92.2%.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000323444200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biotechnology & Applied Microbiology; Medicine, Research & Experimental; SCI(E); 3; ARTICLE
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/392265]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Li, Qingbo,Wang, Wei,Ling, Xiaofeng,et al. Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification[J]. biomed research international,2013.
APA	Li, Qingbo,Wang, Wei,Ling, Xiaofeng,&Wu, Jin Guang.(2013).Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification.biomed research international.
MLA	Li, Qingbo,et al."Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification".biomed research international (2013).