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Preparation of monodisperse PEG hydrogel composite microspheres via microfluidic chip with rounded channels
Yu, Bing ; Cong, Hailin ; Liu, Xuesong ; Ren, Yumin ; Wang, Jilei ; Zhang, Lixin ; Tang, Jianguo ; Ma, Yurong ; Akasaka, Takeshi
刊名journal of micromechanics and microengineering
2013
关键词MICROPARTICLES DEVICE FABRICATION MICROCAPSULES DELIVERY SYSTEM
DOI10.1088/0960-1317/23/9/095016
英文摘要An effective microfluidic method to fabricate monodisperse polyethylene glycol ( PEG) hydrogel composite microspheres with tunable dimensions and properties is reported in this paper. A T-junction microfluidic chip equipped with rounded channels and online photopolymerization system is applied for the microsphere microfabrication. The shape and size of the microspheres are well controlled by the rounded channels and PEG prepolymer/silicon oil flow rate ratios. The obtained PEG/aspirin composite microspheres exhibit a sustained release of aspirin for a wide time range; the obtained PEG/Fe3O4 nanocomposite microspheres exhibit excellent magnetic properties; and the obtained binary PEG/dye composite microspheres show the ability to synchronously load two functional components in the same peanut-shaped or Janus hydrogel particles.; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Instruments & Instrumentation; Materials Science, Multidisciplinary; Mechanics; SCI(E); 3; ARTICLE; 9; 23
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/391166]  
专题化学与分子工程学院
推荐引用方式
GB/T 7714
Yu, Bing,Cong, Hailin,Liu, Xuesong,et al. Preparation of monodisperse PEG hydrogel composite microspheres via microfluidic chip with rounded channels[J]. journal of micromechanics and microengineering,2013.
APA Yu, Bing.,Cong, Hailin.,Liu, Xuesong.,Ren, Yumin.,Wang, Jilei.,...&Akasaka, Takeshi.(2013).Preparation of monodisperse PEG hydrogel composite microspheres via microfluidic chip with rounded channels.journal of micromechanics and microengineering.
MLA Yu, Bing,et al."Preparation of monodisperse PEG hydrogel composite microspheres via microfluidic chip with rounded channels".journal of micromechanics and microengineering (2013).
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