Novel probes for protein chip applications | |
Liao Wei ; Guo Su ; Zhao Xin Sheng | |
刊名 | frontiers in bioscience a journal and virtual library |
2006 | |
英文摘要 | Protein microarrays (protein chips), due to their high throughput, have great potential to reduce the cycle time of drug discovery and to improve the efficiency of medical diagnostics. A great deal of effort has been made to facilitate the development of protein chips, such as the antibody microarrays. High-throughput fabrication of purified high-affinity probes is now one of the bottlenecks for protein microarrays. We discuss here three novel strategies to fabricate probes, namely, single chain antibodies displayed by phage, protein-oligonucleotide conjugates, and aptamers, which are promising in the protein chip technology.; SCI(E); PubMed; 0; REVIEW; 186-97; 11 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/345976] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Liao Wei,Guo Su,Zhao Xin Sheng. Novel probes for protein chip applications[J]. frontiers in bioscience a journal and virtual library,2006. |
APA | Liao Wei,Guo Su,&Zhao Xin Sheng.(2006).Novel probes for protein chip applications.frontiers in bioscience a journal and virtual library. |
MLA | Liao Wei,et al."Novel probes for protein chip applications".frontiers in bioscience a journal and virtual library (2006). |
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