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Novel probes for protein chip applications
Liao Wei ; Guo Su ; Zhao Xin Sheng
刊名frontiers in bioscience a journal and virtual library
2006
英文摘要Protein microarrays (protein chips), due to their high throughput, have great potential to reduce the cycle time of drug discovery and to improve the efficiency of medical diagnostics. A great deal of effort has been made to facilitate the development of protein chips, such as the antibody microarrays. High-throughput fabrication of purified high-affinity probes is now one of the bottlenecks for protein microarrays. We discuss here three novel strategies to fabricate probes, namely, single chain antibodies displayed by phage, protein-oligonucleotide conjugates, and aptamers, which are promising in the protein chip technology.; SCI(E); PubMed; 0; REVIEW; 186-97; 11
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/345976]  
专题化学与分子工程学院
推荐引用方式
GB/T 7714
Liao Wei,Guo Su,Zhao Xin Sheng. Novel probes for protein chip applications[J]. frontiers in bioscience a journal and virtual library,2006.
APA Liao Wei,Guo Su,&Zhao Xin Sheng.(2006).Novel probes for protein chip applications.frontiers in bioscience a journal and virtual library.
MLA Liao Wei,et al."Novel probes for protein chip applications".frontiers in bioscience a journal and virtual library (2006).
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